概述

  • 产品名称
    Anti-LRP3抗体
  • 描述
    兔多克隆抗体to LRP3
  • 经测试应用
    适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Monkey
  • 免疫原

    Synthetic peptide corresponding to Human LRP3 aa 676-693 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    EVGPSGPPLPSGLRDPEC

  • 阳性对照
    • Human skin tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ELISA 1/1000.

靶标

  • 功能
    Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
  • 组织特异性
    Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
  • 序列相似性
    Belongs to the LDLR family.
    Contains 2 CUB domains.
    Contains 4 LDL-receptor class A domains.
  • 细胞定位
    Membrane. Membrane > coated pit.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 105 kDa low-density lipoprotein receptor-related protein antibody
    • CTD-2540B15.13 antibody
    • hLRp105 antibody
    • Low density lipoprotein receptor related protein 3 antibody
    • Low-density lipoprotein receptor-related protein 3 antibody
    • LRP-3 antibody
    • Lrp3 antibody
    • LRP3_HUMAN antibody
    see all

Anti-LRP3 antibody 图像

  • Immunohistochemistry Image of Human Skin (formalin-fixed, paraffin-embedded) stained with LRP3 antibody (ab115197) at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-LRP3 antibody (ab115197)参考文献

ab115197 has not yet been referenced specifically in any publications.

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