概述

  • 产品名称
    Anti-LRFN1抗体
  • 描述
    兔多克隆抗体to LRFN1
  • 经测试应用
    适用于: ICC/IF, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    18 amino acid peptide near the C terminus of Human LRFN1 (Q9P244).

  • 阳性对照
    • Human brain lysate, Mouse brain tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 82 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.

靶标

  • 功能
    Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1.
  • 序列相似性
    Belongs to the LRFN family.
    Contains 1 fibronectin type-III domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 7 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • 结构域
    The PDZ-binding motif is required for neurite outgrowth promotion and for DLG1-, DLG3- and DLG4-binding.
  • 翻译后修饰
    Glycosylated.
  • 细胞定位
    Membrane. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Detected in excitatory, but not inhibitory, synaptic plasma membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA1484 antibody
    • Leucine rich repeat and fibronectin type III domain containing 1 antibody
    • Leucine rich repeat and fibronectin type III domain containing protein 1 antibody
    • Leucine-rich repeat and fibronectin type III domain-containing protein 1 antibody
    • LRFN 1 antibody
    • lrfn1 antibody
    • LRFN1_HUMAN antibody
    • SALM 2 antibody
    • SALM2 antibody
    • Synaptic adhesion like molecule 2 antibody
    • Synaptic adhesion-like molecule 2 antibody
    see all

图片

  • Immunofluorescence of LRFN1 in mouse brain tissue with ab106365 at 20 ug/mL.

  • Lane 1 : Anti-LRFN1 antibody (ab106365) at 1 µg/ml
    Lane 2 : Anti-LRFN1 antibody (ab106365) at 2 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Human brain lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 82 kDa
  • ab106365 at 2.5 µg/ml staining LRFN1 in Mouse brain tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

文献

ab106365 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab106365.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册