概述

  • 产品名称
    Anti-LOXL3抗体
  • 描述
    兔多克隆抗体to LOXL3
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: KRVNAAFYRL LAQRQQHSFG LHGVACVGTE AHLSLCSLEF YRANDTARCP, corresponding to amino acids 223-272 of Human LOXL3.

  • 阳性对照
    • Human placenta tissue; RT 4 and U 251 MG cell lysates, Human tonsil lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab122263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/250.
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 组织特异性
    Expressed in many tissues, the highest levels among the tissues studied being seen in the placenta, heart, ovary, testis, small intestine and spleen.
  • 序列相似性
    Belongs to the lysyl oxidase family.
    Contains 4 SRCR domains.
  • 翻译后修饰
    The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
  • 细胞定位
    Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LOXL antibody
    • Loxl3 antibody
    • LOXL3_HUMAN antibody
    • Lysyl oxidase homolog 3 antibody
    • Lysyl oxidase like 3 antibody
    • Lysyl oxidase-like protein 3 antibody
    see all

Anti-LOXL3 antibody 图像

  • ab122263, at 1/30, staining LOXL3 in paraffin embedded Human placenta tissue by Immunohistochemistry.
  • All lanes : Anti-LOXL3 antibody (ab122263) at 1/250 dilution

    Lane 1 : RT 4 cell lysate
    Lane 2 : U 251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique

Anti-LOXL3 antibody (ab122263)参考文献

This product has been referenced in:
  • Mižíková I  et al. Collagen and elastin cross-linking is altered during aberrant late lung development associated with hyperoxia. Am J Physiol Lung Cell Mol Physiol 308:L1145-58 (2015). Read more (PubMed: 25840994) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab122263.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册