概述

  • 产品名称
  • 描述
    兔多克隆抗体to LOX
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the Center region of Human LOX conjugated to KLH (NP_002308.2).

  • 阳性对照
    • MDA-MB468 cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab94991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 47 kDa.

靶标

  • 功能
    Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
  • 组织特异性
    Heart, placenta, skeletal muscle, kidney, lung and pancreas.
  • 疾病相关
    Defects in LOX may be a cause of cutis laxa autosomal recessive type 1 (ARCL1) [MIM:219100].
  • 序列相似性
    Belongs to the lysyl oxidase family.
  • 翻译后修饰
    The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
  • 细胞定位
    Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • lox antibody
    • LYOX antibody
    • LYOX_HUMAN antibody
    • Lysyl oxidase antibody
    • MGC105112 antibody
    • Protein lysine 6 oxidase antibody
    • Protein-lysine 6-oxidase antibody
    see all

Anti-LOX antibody 图像

  • Anti-LOX antibody (ab94991) at 1/100 dilution + MDA-MB468 cell line lysates at 35 µg

    Predicted band size : 47 kDa

实验方案

Anti-LOX antibody (ab94991)参考文献

ab94991 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94991.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册