概述

  • 产品名称Anti-LOX抗体
    参阅全部 LOX 一抗
  • 描述
    兔多克隆抗体to LOX
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the Center region of Human LOX conjugated to KLH (NP_002308.2).

  • 阳性对照
    • MDA-MB468 cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab94991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 47 kDa.

靶标

  • 功能Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
  • 组织特异性Heart, placenta, skeletal muscle, kidney, lung and pancreas.
  • 疾病相关Defects in LOX may be a cause of cutis laxa autosomal recessive type 1 (ARCL1) [MIM:219100].
  • 序列相似性Belongs to the lysyl oxidase family.
  • 翻译后修饰The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
  • 细胞定位Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • lox antibody
    • LYOX antibody
    • LYOX_HUMAN antibody
    • Lysyl oxidase antibody
    • MGC105112 antibody
    • Protein lysine 6 oxidase antibody
    • Protein-lysine 6-oxidase antibody
    see all

Anti-LOX antibody 图像

  • Anti-LOX antibody (ab94991) at 1/100 dilution + MDA-MB468 cell line lysates at 35 µg

    Predicted band size : 47 kDa

Anti-LOX antibody (ab94991)参考文献

ab94991 has not yet been referenced specifically in any publications.

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