概述

  • 产品名称Anti-LMX1b抗体
    参阅全部 LMX1b 一抗
  • 描述
    兔多克隆抗体to LMX1b
  • 特异性ab70174 detects endogenous levels of total LMX1b protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide: DLLSSVSPDE SDSVKSEDED GDMKPAKGQG , corresponding to internal sequence amino acids 151-180 of Human LMX1b

  • 阳性对照
    • Jurkat, 293 and HUVEC cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab70174 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
ELISA 1/40000.

靶标

  • 功能Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
  • 组织特异性Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
  • 疾病相关Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.
  • 序列相似性Contains 1 homeobox DNA-binding domain.
    Contains 2 LIM zinc-binding domains.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LIM homeo box transcription factor 1 beta antibody
    • LIM homeobox transcription factor 1 beta antibody
    • LIM homeobox transcription factor 1-beta antibody
    • LIM-homeobox protein 1.2 antibody
    • LIM/homeobox protein 1.2 antibody
    • LIM/homeobox protein LMX1B antibody
    • LMX 1.2 antibody
    • LMX-1.2 antibody
    • LMX1.2 antibody
    • LMX1B antibody
    • LMX1B_HUMAN antibody
    • MGC138325 antibody
    • MGC142051 antibody
    • NPS 1 antibody
    • NPS1 antibody
    see all

Anti-LMX1b antibody 图像

  • All lanes : Anti-LMX1b antibody (ab70174) at 1/500 dilution

    Lane 1 : Jurkat cell extracts
    Lane 2 : 293 cell extracts
    Lane 3 : HUVEC cell extracts
    Lane 4 : 293 cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 41 kDa
    Observed band size : 41 kDa

Anti-LMX1b antibody (ab70174)参考文献

ab70174 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab70174.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"