Anti-LMO2抗体- ChIP Grade (ab72841)


  • 产品名称Anti-LMO2抗体- ChIP Grade
    参阅全部 LMO2 一抗
  • 描述
    兔多克隆抗体to LMO2 - ChIP Grade
  • 经测试应用适用于: ChIP, WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Cow, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal residues 1-100 of human LMO2. [Swiss-Prot# P25791]

  • 阳性对照
    • Ramos Whole Cell Extracts.




Our Abpromise guarantee covers the use of ab72841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ChIP Use at an assay dependent dilution.
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 18 kDa).


  • 功能Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
  • 疾病相关Note=A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.
  • 序列相似性Contains 2 LIM zinc-binding domains.
  • 结构域The second LIM zinc-binding domain interacts with KDM5A.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cysteine rich protein TTG 2 antibody
    • Cysteine rich protein TTG2 antibody
    • Cysteine-rich protein TTG-2 antibody
    • LIM domain only 2 (rhombotin like 1) antibody
    • LIM domain only 2 antibody
    • LIM domain only protein 2 antibody
    • LMO 2 antibody
    • LMO-2 antibody
    • lmo2 antibody
    • RBTN 2 antibody
    • RBTN L1 antibody
    • RBTN2 antibody
    • RBTN2_HUMAN antibody
    • RBTNL 1 antibody
    • RBTNL1 antibody
    • RHOM 2 antibody
    • RHOM2 antibody
    • Rhombotin 2 antibody
    • Rhombotin like 1 antibody
    • Rhombotin-2 antibody
    • Rhombotin2 antibody
    • T cell translocation gene 2 antibody
    • T cell translocation protein 2 antibody
    • T-cell translocation protein 2 antibody
    • TTG 2 antibody
    • TTG2 antibody
    see all

Anti-LMO2 antibody - ChIP Grade 图像

  • Anti-LMO2 antibody - ChIP Grade (ab72841) at 0.5 mg/ml + Ramos whole cell lysate

    Predicted band size : 18 kDa
    Observed band size : 24 kDa (why is the actual band size different from the predicted?)
  • ab72841 used undiluted in ChIP analysis, incubated for 16 hours at 4°C.
    Nuclear cell lysate prepared from mouse haematopoietic progenitor cell line HPC-7.
    Cross-linking (X-ChIP) performed by using 1% formaldehyde for 10 minutes.
    Detection step: Real time PCR.
    Negative control: A regultory element which is an open region of chromatin but is devoid of this transcription factor.

    See Abreview

Anti-LMO2 antibody - ChIP Grade (ab72841)参考文献

ab72841 has not yet been referenced specifically in any publications.

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The antibody ab26096 has not been tested in Chip application so I am sorry we are unable to confirm its use. This however does not means the antibody cannot be used it only means we do not have tested data. If you ...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application ChIP
Sample Mouse Cell lysate - nuclear (haematopoietic progenitor cell line HPC-7)
Specification haematopoietic progenitor cell line HPC-7
Type Cross-linking (X-ChIP)
Duration of cross-linking step: 10 minute(s) and 0 second(s)
Specification of the cross-linking agent: 1% formaldehyde
Detection step Real-time PCR
Positive control i) a competitors antibody known to work
ii) a regulatory element known to bind this transcription factor
Negative control a regultory element which is an open region of chromatin but is devoid of this transcription factor

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提交于 Feb 18 2010