概述

  • 产品名称
    Anti-LMO2抗体[1A9-3D11]
    参阅全部 LMO2 一抗
  • 描述
    小鼠单克隆抗体[1A9-3D11] to LMO2
  • 宿主
    Mouse
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to human LMO2.

  • 阳性对照
    • Human tonsil.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: Tissue culture supernatant
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 纯化说明
    ab64139 was purified from ascites fluid using Protein A.
  • 克隆
    单克隆
  • 克隆编号
    1A9-3D11
  • 同种型
    IgG1
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab64139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: 1/100 for 30 min at room temperature. Staining of formalin fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
    • 疾病相关
      Note=A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.
    • 序列相似性
      Contains 2 LIM zinc-binding domains.
    • 结构域
      The second LIM zinc-binding domain interacts with KDM5A.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cysteine rich protein TTG 2 antibody
      • Cysteine rich protein TTG2 antibody
      • Cysteine-rich protein TTG-2 antibody
      • LIM domain only 2 (rhombotin like 1) antibody
      • LIM domain only 2 antibody
      • LIM domain only protein 2 antibody
      • LMO 2 antibody
      • LMO-2 antibody
      • lmo2 antibody
      • RBTN 2 antibody
      • RBTN L1 antibody
      • RBTN2 antibody
      • RBTN2_HUMAN antibody
      • RBTNL 1 antibody
      • RBTNL1 antibody
      • RHOM 2 antibody
      • RHOM2 antibody
      • Rhombotin 2 antibody
      • Rhombotin like 1 antibody
      • Rhombotin-2 antibody
      • Rhombotin2 antibody
      • T cell translocation gene 2 antibody
      • T cell translocation protein 2 antibody
      • T-cell translocation protein 2 antibody
      • TTG 2 antibody
      • TTG2 antibody
      see all

    图片

    • ab64139 staining LMO2 in human lymph node tissue section by Immunohistochemistry(Formalin/PFA-fixed paraffin-embedded sections). Tissue underwent fixation in formaldehyde, antigen retrieval in Target Retrieval Solution and blocking in 100% serum for 10 minutes at 25°C. The primary antibody was diluted, 1/700 and incubated with sample for 1 hour at 25°C. A polymer linked mouse polyclonal to mouse IgG1 was used undiluted, as secondary.

    文献

    This product has been referenced in:
    • Funk KE  et al. Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake. J Biol Chem 290:21652-62 (2015). Read more (PubMed: 26126828) »

    See 1 Publication for this product

    客户评价及客户问答

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample
    Human Tissue sections (Lymph node)
    Specification
    Lymph node
    Fixative
    Formaldehyde
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: Target Retrieval Solution,Dako
    Permeabilization
    No
    Blocking step
    Novolink Protein Block, Novocastra, Leica Microsystems Inc. as blocking agent for 10 minute(s) · Concentration: 100% · Temperature: 25°C
    Username

    Dr. Hajnalka Rajnai

    Verified customer

    提交于 Apr 01 2010

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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