概述

  • 产品名称Anti-LLGL2抗体
    参阅全部 LLGL2 一抗
  • 描述
    兔多克隆抗体to LLGL2
  • 特异性Reacts specifically with human 113 kDa protein.
  • 经测试应用适用于: WB, IHC-Frmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from N terminal domain of human LLGL2 protein

性能

应用

Our Abpromise guarantee covers the use of ab73304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 113 kDa.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 功能Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
  • 序列相似性Belongs to the WD repeat L(2)GL family.
    Contains 14 WD repeats.
  • 翻译后修饰Phosphorylated at Ser-653 by PRKCI. Phosphorylation is enhanced during cell polarization induced by calcium. Phosphorylation may occur during the cell-cell contact-induced cell polarization and may contribute to the segregation of LLGL2 from the PRKCI/aPKC and PARD6B/Par-6 complex.
  • 细胞定位Cytoplasm. Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HGL antibody
    • Human giant larvae homolog antibody
    • L2GL2 antibody
    • L2GL2_HUMAN antibody
    • Lethal 2 giant larvae protein homolog 2 antibody
    • Lethal giant larvae homolog 2 antibody
    • Lethal(2) giant larvae protein homolog 2 antibody
    • LGL2 antibody
    • LLGL2 antibody
    see all

Anti-LLGL2 antibody (ab73304)参考文献

ab73304 has not yet been referenced specifically in any publications.

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