Anti-Liver Carboxylesterase 1/CES1抗体(ab115280)
Key features and details
- Goat polyclonal to Liver Carboxylesterase 1/CES1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Liver Carboxylesterase 1/CES1抗体
参阅全部 Liver Carboxylesterase 1/CES1 一抗 -
描述
山羊多克隆抗体to Liver Carboxylesterase 1/CES1 -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Chimpanzee, Macaque monkey, Orangutan -
免疫原
Synthetic peptide corresponding to Human Liver Carboxylesterase 1/CES1 aa 500-600 (internal sequence).
Database link: P23141 -
阳性对照
- Recombinant Human Liver Carboxylesterase 1/CES1 protein (ab114347) can be used as a positive control in WB. Human lung tissue. Human liver lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Constituents: 99% Tris buffered saline, 0.02% Sodium chloride, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab115280于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 63 kDa.
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IHC-P |
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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WB
Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 63 kDa. |
IHC-P
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. -
组织特异性
Expressed predominantly in liver with lower levels in heart and lung. -
序列相似性
Belongs to the type-B carboxylesterase/lipase family. -
翻译后修饰
Contains sialic acid.
Cleavage of the signal sequence can occur at 2 positions, either between Trp-17 and Gly-18 or between Gly-18 and His-19. -
细胞定位
Endoplasmic reticulum lumen. - Information by UniProt
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数据库链接
- Entrez Gene: 1066 Human
- Omim: 114835 Human
- SwissProt: P23141 Human
- Unigene: 558865 Human
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别名
- ACAT antibody
- Acyl coenzyme A cholesterol acyltransferase antibody
- Acyl-coenzyme A:cholesterol acyltransferase antibody
see all
图片
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Human Lung formalin-fixed, paraffin-embedded tissue stained with ab115280 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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Anti-Liver Carboxylesterase 1/CES1 antibody (ab115280) at 0.03 µg/ml + Human Liver lysate in RIPA buffer (incubation time: 1 hour) at 35 µg
Developed using the ECL technique.
Predicted band size: 63 kDa
数据表及文件
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Datasheet download
文献 (0)
ab115280 尚未被引用在任何文献中。