重组
RabMAb

Anti-Liver Arginase抗体[EPR6671(B)] (ab124917)

概述

  • 产品名称
    Anti-Liver Arginase抗体[EPR6671(B)]
    参阅全部 Liver Arginase 一抗
  • 描述
    兔单克隆抗体[EPR6671(B)] to Liver Arginase
  • 经测试应用
    适用于: WB, IPmore details
    不适用于: ICC/IF or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human liver Arginase

  • 阳性对照
    • Fetal liver and mouse liver lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

应用

Our Abpromise guarantee covers the use of ab124917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 35 kDa.
IP 1/10 - 1/100.
  • 应用说明
    Is unsuitable for ICC/IF or IHC-P.
  • 靶标

    • 通路
      Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
    • 疾病相关
      Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
    • 序列相似性
      Belongs to the arginase family.
    • 细胞定位
      Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A I antibody
      • Al antibody
      • ARG 1 antibody
      • arg1 antibody
      • ARGI1_HUMAN antibody
      • Arginase 1 antibody
      • Arginase liver antibody
      • Arginase type I antibody
      • Arginase, liver antibody
      • Arginase-1 antibody
      • Arginase1 antibody
      • Liver type arginase antibody
      • Liver-type arginase antibody
      • Type I arginase antibody
      see all

    图片

    • All lanes : Anti-Liver Arginase antibody [EPR6671(B)] (ab124917) at 1/1000 dilution

      Lane 1 : Human fetal liver lysate
      Lane 2 : Mouse liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 35 kDa

    文献

    This product has been referenced in:
    • Ando Y  et al. Platelet Supernatant Suppresses LPS-Induced Nitric Oxide Production from Macrophages Accompanied by Inhibition of NF-?B Signaling and Increased Arginase-1 Expression. PLoS One 11:e0162208 (2016). Read more (PubMed: 27588757) »
    • Xia N  et al. Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese Mice. Arterioscler Thromb Vasc Biol 36:78-85 (2016). Read more (PubMed: 26586660) »

    See all 2 Publications for this product

    客户评价及客户问答

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Mouse Cell lysate - whole cell (Bone Marrow-Derived Macrophages)
    Gel Running Conditions
    Reduced Denaturing (10% polyacrylamide gel)
    Loading amount
    160000 cells
    Treatment
    20 ng/mL mouse IL-4 for 24 hours
    Specification
    Bone Marrow-Derived Macrophages
    Blocking step
    Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Username

    祐介 安藤

    Verified customer

    提交于 Nov 16 2016

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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