RabMAb

Anti-Liver Arginase抗体[EPR6671(B)] (ab124917)

概述

  • 产品名称Anti-Liver Arginase抗体[EPR6671(B)]
    参阅全部 Liver Arginase 一抗
  • 描述
    兔单克隆抗体[EPR6671(B)] to Liver Arginase
  • 经测试应用适用于: WB, IPmore details
    不适用于: ICC/IF or IHC-P
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human liver Arginase

  • 阳性对照
    • Fetal liver and mouse liver lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab124917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 35 kDa.
IP 1/10 - 1/100.
  • 应用说明Is unsuitable for ICC/IF or IHC-P.
  • 靶标

    • 通路Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
    • 疾病相关Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
    • 序列相似性Belongs to the arginase family.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A I antibody
      • Al antibody
      • ARG 1 antibody
      • arg1 antibody
      • ARGI1_HUMAN antibody
      • Arginase 1 antibody
      • Arginase liver antibody
      • Arginase type I antibody
      • Arginase, liver antibody
      • Arginase-1 antibody
      • Arginase1 antibody
      • Liver type arginase antibody
      • Liver-type arginase antibody
      • Type I arginase antibody
      see all

    Anti-Liver Arginase antibody [EPR6671(B)] 图像

    • All lanes : Anti-Liver Arginase antibody [EPR6671(B)] (ab124917) at 1/1000 dilution

      Lane 1 : Human fetal liver lysate
      Lane 2 : Mouse liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 35 kDa

    Anti-Liver Arginase antibody [EPR6671(B)] (ab124917)参考文献

    This product has been referenced in:
    • Ando Y  et al. Platelet Supernatant Suppresses LPS-Induced Nitric Oxide Production from Macrophages Accompanied by Inhibition of NF-?B Signaling and Increased Arginase-1 Expression. PLoS One 11:e0162208 (2016). Read more (PubMed: 27588757) »

    See 1 Publication for this product

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Sample Mouse Cell lysate - whole cell (Bone Marrow-Derived Macrophages)
    Gel Running Conditions Reduced Denaturing (10% polyacrylamide gel)
    Loading amount 160000 cells
    Treatment 20 ng/mL mouse IL-4 for 24 hours
    Specification Bone Marrow-Derived Macrophages
    Blocking step Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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    祐介 安藤

    Verified customer

    提交于 Nov 16 2016

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"