概述

  • 产品名称Anti-liver Arginase抗体
    参阅全部 Liver Arginase 一抗
  • 描述
    兔多克隆抗体to liver Arginase
  • 经测试应用适用于: WB, IP, ELISA, Conjugationmore details
  • 种属反应性
    与反应: Cow
  • 免疫原

    Arginase [Bovine Liver]

  • 常规说明


    Suitable for immunoblotting (western or dot blot), ELISA, immunoprecipitation, conjugation and most immunological methods requiring high titer and specificity.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
  • Primary antibody说明Suitable for immunoblotting (western or dot blot), ELISA, immunoprecipitation, conjugation and most immunological methods requiring high titer and specificity.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab2111 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Use under non reducing condition. Detects a band of approximately 120 kDa.
IP Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
Conjugation Use at an assay dependent dilution.

靶标

  • 通路Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
  • 疾病相关Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
  • 序列相似性Belongs to the arginase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 别名
    • A I antibody
    • Al antibody
    • ARG 1 antibody
    • arg1 antibody
    • ARGI1_HUMAN antibody
    • Arginase 1 antibody
    • Arginase liver antibody
    • Arginase type I antibody
    • Arginase, liver antibody
    • Arginase-1 antibody
    • Arginase1 antibody
    • Liver type arginase antibody
    • Liver-type arginase antibody
    • Type I arginase antibody
    see all

Anti-liver Arginase antibody (ab2111)参考文献

This product has been referenced in:
  • Nelin LD  et al. MKP-1 switches arginine metabolism from nitric oxide synthase to arginase following endotoxin challenge. Am J Physiol Cell Physiol 293:C632-40 (2007). Read more (PubMed: 17442735) »
  • Buchwalow IB  et al. Compartmentalization of NO signaling cascade in skeletal muscles. Biochem Biophys Res Commun 330:615-21 (2005). Read more (PubMed: 15796928) »

See all 2 Publications for this product

Product Wall

Thank you for your enquiry. This antibody has only been tested to react in cow, so we can not guarantee that this antibody will work with mouse samples. Typically, homology over 85% is a good measure of whether the antibody will work in that species or...

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Thank you for your enquiry. All the information we have on species cross reactivity is specified on the datasheet, these are updated as soon as any new information is brought to our attention. As far as we are aware, cross reactivity with human has not...

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The antibody is raised against the whole native enzyme. It is reported Arginase II is expressed low in liver. We have not tested it with mouse or human and we are unable to predict the cross reactivity. The expected band size on SDS-PAGE is 120 kDa un...

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This polyclonal antibody reacts with arginase from most animal tissues. It quite possibly has cross-reactivity with human arginase. However, until it has been tested, we can't say for sure.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"