概述

  • 产品名称
    Anti-liver Arginase抗体
    参阅全部 Liver Arginase 一抗
  • 描述
    山羊多克隆抗体to liver Arginase
  • 经测试应用
    适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide:

    C-NHKPETDYLKPPK

    , corresponding to C terminal amino acids 311-323 of Rat liver Arginase (UniProt P07824).

  • 阳性对照
    • Human liver tissue; Rat liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab118884 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/32000.
WB Use a concentration of 0.03 - 0.3 µg/ml. Predicted molecular weight: 35 kDa.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 通路
    Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
  • 疾病相关
    Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia.
  • 序列相似性
    Belongs to the arginase family.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A I antibody
    • Al antibody
    • ARG 1 antibody
    • arg1 antibody
    • ARGI1_HUMAN antibody
    • Arginase 1 antibody
    • Arginase liver antibody
    • Arginase type I antibody
    • Arginase, liver antibody
    • Arginase-1 antibody
    • Arginase1 antibody
    • Liver type arginase antibody
    • Liver-type arginase antibody
    • Type I arginase antibody
    see all

图片

  • Anti-liver Arginase antibody (ab118884) at 0.03 µg/ml + Rat liver lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 35 kDa


    Exposure time : 1 hour
  • Formalin fixed, paraffin embedded Human liver tissue stained with ab11884 at 3.75 µg/ml.

文献

This product has been referenced in:
  • Carpino G  et al. Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway. PLoS One 11:e0157246 (2016). Read more (PubMed: 27310371) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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