概述

  • 产品名称
  • 描述
    兔多克隆抗体to LIPT2
  • 经测试应用
    适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: CAIGVRCGRHITSHGLALNCSTDLTWFEHIVPCGLVGTGVTSLSKELQRH VTVEEVMPPFLVA FKEIYKCTLISEDS, corresponding to amino acids 153-229 of Human LIPT2. (A6NK58).

  • 阳性对照
    • Human rectum tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20ºC.
  • 存储溶液
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab122641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 功能
    Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  • 通路
    Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.
  • 序列相似性
    Belongs to the lipB family.
  • 细胞定位
    Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EC 2.3.1.181 antibody
    • FCT2 antibody
    • Lipoate-protein ligase B antibody
    • Lipoyl(octanoyl) transferase 2 (putative) antibody
    • Lipoyl/octanoyl transferase antibody
    • Lipt2 antibody
    • LIPT2_HUMAN antibody
    • mitochondrial antibody
    • Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase antibody
    • OTTHUMP00000230589 antibody
    • OTTHUMP00000230590 antibody
    • OTTHUMP00000230591 antibody
    • Putative lipoyltransferase 2 antibody
    • Putative lipoyltransferase 2, mitochondrial antibody
    • Putative octanoyltransferase, mitochondrial antibody
    • SLC22A16 antibody
    see all

图片

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in vesicles. Recommended concentration of ab122641 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122641, at 1/20, staining LIPT2 in paraffin embedded Human rectum by Immunohistochemistry.

文献

ab122641 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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