Anti-LIPG抗体(ab24447)
Key features and details
- Rabbit polyclonal to LIPG
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-LIPG抗体 -
描述
兔多克隆抗体to LIPG -
宿主
Rabbit -
特异性
ab24447 reacts with Endothelial lipase. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide surrounding amino acid 22 of human Endothelial Lipase. (Peptide available as ab53323.)
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常规说明
This product is manufactured by BioVision, an Abcam company and was previously called 3657 Endothelial Lipase Antibody. 3657-100 is the same size as the 100 µg size of ab24447.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab24447于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 57 kDa.
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说明 |
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WB
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 57 kDa. |
靶标
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功能
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin. -
组织特异性
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocyte and osteosarcoma cell lines. Not detected in heart, brain and muscle. -
序列相似性
Belongs to the AB hydrolase superfamily. Lipase family.
Contains 1 PLAT domain. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 9388 Human
- Omim: 603684 Human
- SwissProt: Q9Y5X9 Human
- Unigene: 465102 Human
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别名
- EDL antibody
- EL antibody
- Endothelial cell-derived lipase antibody
see all
图片
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Anti-LIPG antibody (ab24447) + HepG2 lysate
Observed band size: 57 kDa why is the actual band size different from the predicted?
Use ab24447 at 1-4µg/ml.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab24447 被引用在 3 文献中.
- Cheng X et al. Identification of potential functional variants and genes at 18q21.1 associated with the carcinogenesis of colorectal cancer. PLoS Genet 18:e1010050 (2022). PubMed: 35108261
- Cadenas C et al. LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer. Int J Cancer 145:901-915 (2019). PubMed: 30653260
- Kimura N et al. Multiple endocrine neoplasia type 1-associated cystic pancreatic endocrine neoplasia and multifocal cholesterol granulomas. Pathol Int 60:321-5 (2010). IHC-P ; Human . PubMed: 20403035