概述

  • 产品名称Anti-LIMPII抗体
    参阅全部 LIMPII 一抗
  • 描述
    兔多克隆抗体to LIMPII
  • 经测试应用适用于: WB, IP, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Mouse LIMPII (C terminal).
    Database link: O35114

  • 阳性对照
    • Rat cardiac fibroblast lysate, 3T3 mouse fibroblast lysate, HEPG2 human liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab16522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 85 kDa.
IP 1/100.
IHC-P Use at an assay dependent concentration.
ICC/IF 1/50 - 1/250.

靶标

  • 功能Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
    (Microbial infection) Acts as a receptor for enterovirus 71.
  • 疾病相关Epilepsy, progressive myoclonic 4, with or without renal failure
    Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
  • 序列相似性Belongs to the CD36 family.
  • 细胞定位Lysosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 85 kDa lysosomal membrane sialoglycoprotein antibody
    • 85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2 antibody
    • AMRF antibody
    • CD36 antibody
    • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) antibody
    • CD36 antigen antibody
    • CD36 antigen-like 2 antibody
    • CD36L2 antibody
    • EPM4 antibody
    • HLGP85 antibody
    • LGP85 antibody
    • LIMP 2 antibody
    • LIMP II antibody
    • LIMP2 antibody
    • LIMPII antibody
    • Lysosomal integral membrane protein II antibody
    • Lysosome membrane protein 2 antibody
    • Lysosome membrane protein II antibody
    • OTTHUMP00000160590 antibody
    • OTTHUMP00000219176 antibody
    • Scarb2 antibody
    • Scavenger receptor class B member 2 antibody
    • Scavenger receptor class B, member 2 antibody
    • SCRB2_HUMAN antibody
    • SR BII antibody
    • SRBII antibody
    see all

Anti-LIMPII antibody 图像

  • All lanes : Anti-LIMPII antibody (ab16522)

    Lane 1 : Rat cardiac fibroblasts (RCF)
    Lane 2 : 3T3 mouse fibroblasts
    Lane 3 : Long hond canine lung lysate
    Lane 4 : RCF treated with angiotensin II
    Lane 5 : RCF treated with H2O2
    Lane 6 : HEPG2 human liver lysate
    ECL 40 minute exposure.
  • Staining of LIMP II in rat infarctzone tissue using ab16522 with a DAB detection system.
  • Immunocytochemistry/Immunofluorescence analysis of Hela cells labelling LIMPII/Ipg85 with ab16522 (Green) at 1/50.00000-1/250.00000 dilution.

Anti-LIMPII antibody (ab16522)参考文献

This product has been referenced in:
  • Simón D  et al. Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles. FEBS Lett : (2011). WB ; Human . Read more (PubMed: 22138183) »
  • Conde-Vancells J  et al. Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl 4:416-425 (2010). WB ; Rat . Read more (PubMed: 20535238) »

See all 2 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunoprecipitation
Sample Human Cell lysate - other (B cell line, crude membranes)
Total protein in input 5000 µg
Specification B cell line, crude membranes
Immuno-precipitation step Other - rabbit IgG Dynabeads
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提交于 Mar 17 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"