概述

  • 产品名称Anti-LIMPII抗体
    参阅全部 LIMPII 一抗
  • 描述
    兔多克隆抗体to LIMPII
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 16 amino acid synthetic peptide from near the center of Human LIMP2 (AAH21892).

  • 阳性对照
    • Human skeletal muscle tissue and lysate.

性能

应用

Our Abpromise guarantee covers the use of ab106519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
    (Microbial infection) Acts as a receptor for enterovirus 71.
  • 疾病相关Epilepsy, progressive myoclonic 4, with or without renal failure
    Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
  • 序列相似性Belongs to the CD36 family.
  • 细胞定位Lysosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 85 kDa lysosomal membrane sialoglycoprotein antibody
    • 85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2 antibody
    • AMRF antibody
    • CD36 antibody
    • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) antibody
    • CD36 antigen antibody
    • CD36 antigen-like 2 antibody
    • CD36L2 antibody
    • EPM4 antibody
    • HLGP85 antibody
    • LGP85 antibody
    • LIMP 2 antibody
    • LIMP II antibody
    • LIMP2 antibody
    • LIMPII antibody
    • Lysosomal integral membrane protein II antibody
    • Lysosome membrane protein 2 antibody
    • Lysosome membrane protein II antibody
    • OTTHUMP00000160590 antibody
    • OTTHUMP00000219176 antibody
    • Scarb2 antibody
    • Scavenger receptor class B member 2 antibody
    • Scavenger receptor class B, member 2 antibody
    • SCRB2_HUMAN antibody
    • SR BII antibody
    • SRBII antibody
    see all

Anti-LIMPII antibody 图像



  • Predicted band size : 54 kDa

    Western blot analysis of LIMP2 in mouse liver tissue lysate with LIMP2 antibody at 1 µg/mL in (A) the absence and (B) presence of blocking peptide.

  • All lanes : Anti-LIMPII antibody (ab106519) at 1 µg/ml

    Lane 1 : Human skeletal muscle tissue lysate
    Lane 2 : Human skeletal muscle tissue lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 54 kDa
    Despite its predicted molecular weight, LIMPII runs at approximately 80 – 85 kDa in SDS-PAGE.

Anti-LIMPII antibody (ab106519)参考文献

This product has been referenced in:
  • McNeill A  et al. Ambroxol improves lysosomal biochemistry in glucocerebrosidase mutation-linked Parkinson disease cells. Brain 137:1481-95 (2014). WB ; Human . Read more (PubMed: 24574503) »
  • Su PY  et al. Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells. BMC Microbiol 12:162 (2012). WB . Read more (PubMed: 22853823) »

See all 2 Publications for this product

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