Anti-LIM kinase 2抗体(ab97766)

概述

  • 产品名称Anti-LIM kinase 2抗体
    参阅全部 LIM kinase 2 一抗
  • 描述
    兔多克隆抗体to LIM kinase 2
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant protein fragment with a sequence corresponding to a region within amino acids 294 and 665 of Human LIM kinase 2 (AAH13051).

  • 阳性对照
    • Molt-4 and Raji cell lines. 293T whole cell lysate. Paraffin-embedded CA922 xenograft.

性能

应用

Our Abpromise guarantee covers the use of ab97766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 78 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.
  • 组织特异性Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
    Contains 2 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated on serine and/or threonine residues by ROCK1.
  • 细胞定位Cytoplasm. Nucleus. Isoform LIMK2a is distributed in the cytoplasm and the nucleus and Cytoplasm. Nucleus. Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LIM domain kinase 2 antibody
    • LIMK 2 antibody
    • LIMK-2 antibody
    • Limk2 antibody
    • LIMK2_HUMAN antibody
    see all

Anti-LIM kinase 2 antibody 图像

  • Anti-LIM kinase 2 antibody (ab97766) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 78 kDa
  • ab97766, at 1/500, staining paraffin-embedded CA922 xenograft by Immunohistochemistry.

Anti-LIM kinase 2 antibody (ab97766)参考文献

ab97766 has not yet been referenced specifically in any publications.

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