Anti-LIM kinase 2抗体(ab39659)

概述

  • 产品名称Anti-LIM kinase 2抗体
    参阅全部 LIM kinase 2 一抗
  • 描述
    兔多克隆抗体to LIM kinase 2
  • 特异性ab39659 detects endogenous levels of total LIM kinase 2 protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide (non-phosphopeptide derived) from Human LIM kinase 2 around the phosphorylation site of Threonine 505.

  • 阳性对照
    • NIH/3T3 (Mouse embryonic fibroblast cell line) cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab39659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
ELISA 1/4000.

靶标

  • 功能Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.
  • 组织特异性Highest expression in the placenta; moderate level in liver, lung, kidney, and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver, colon, stomach, and spleen, while in brain, kidney, and placenta LIMK2b is the dominant form. In adult lung, both LIMK2a and LIMK2b is nearly equally observed.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
    Contains 2 LIM zinc-binding domains.
    Contains 1 PDZ (DHR) domain.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated on serine and/or threonine residues by ROCK1.
  • 细胞定位Cytoplasm. Nucleus. Isoform LIMK2a is distributed in the cytoplasm and the nucleus and Cytoplasm. Nucleus. Isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • LIM domain kinase 2 antibody
    • LIMK 2 antibody
    • LIMK-2 antibody
    • Limk2 antibody
    • LIMK2_HUMAN antibody
    see all

Anti-LIM kinase 2 antibody 图像

  • All lanes : Anti-LIM kinase 2 antibody (ab39659) at 1/500 dilution

    Lane 1 : NIH/3T3 with UV
    Lane 2 : A2780 without UV


    Predicted band size : 72 kDa
    Observed band size : 72 kDa

Anti-LIM kinase 2 antibody (ab39659)参考文献

ab39659 has not yet been referenced specifically in any publications.

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