概述

  • 产品名称Anti-LILRB2抗体
    参阅全部 LILRB2 一抗
  • 描述
    小鼠单克隆抗体to LILRB2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 22-599 of Human LILRB2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
    • 组织特异性Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.
    • 序列相似性Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
    • 结构域Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
    • 翻译后修饰Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD85 antigen-like family member D antibody
      • CD85d antibody
      • CD85d antigen antibody
      • ILT 4 antibody
      • ILT-4 antibody
      • ILT4 antibody
      • Immunoglobulin like transcript 4 antibody
      • Immunoglobulin-like transcript 4 antibody
      • Leukocyte immunoglobulin like receptor 2 antibody
      • Leukocyte immunoglobulin like receptor subfamily B member 2 antibody
      • Leukocyte immunoglobulin-like receptor 2 antibody
      • Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody
      • Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 antibody
      • LILRA6 antibody
      • LILRB2 antibody
      • LIR 2 antibody
      • LIR-2 antibody
      • LIR2 antibody
      • LIRb antibody
      • LIRB2_HUMAN antibody
      • MIR 10 antibody
      • MIR-10 antibody
      • MIR10 antibody
      • Monocyte/macrophage immunoglobulin like receptor 10 antibody
      • Monocyte/macrophage immunoglobulin-like receptor 10 antibody
      see all

    Anti-LILRB2 antibody 图像



    • Predicted band size : 65 kDa
      LILRB2 antibody (ab56696) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-LILRB2 antibody (ab56696)参考文献

    This product has been referenced in:
    • Isnardi I  et al. Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones. Blood 115:5026-36 (2010). Read more (PubMed: 20231422) »

    See 1 Publication for this product

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Mouse Cell (Mouse Stem Cells)
    Specification Mouse Stem Cells
    Fixative Paraformaldehyde
    Permeabilization Yes - Triton-x
    Blocking step Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Username

    Abcam user community

    Verified customer

    提交于 May 02 2012

    We are sorry to here that you are unable to take advantage of our abreview program. Unfortunately we do not offer the types of programs that you have mentioned (free sample/deduction). If in the future you would like to use our abreview program please ...

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    Thank you very much for your interest in ab56696. To our knowledge, ab56696 has not been tested in IHC. Therefore, I can offer a discount off a future purchase if you buy ab56696 now, test it in IHC and submit feedback to us in the form of an Abreview....

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"