Anti-LILRB2抗体[27D6] (FITC) (ab95819)

概述

  • 产品名称Anti-LILRB2抗体[27D6] (FITC)
    参阅全部 LILRB2 一抗
  • 描述
    大鼠单克隆抗体[27D6] to LILRB2 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    LILRB2-transfected RBL cells

  • 阳性对照
    • Normal Human peripheral blood cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS, BSA, Gelatin, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号27D6
  • 同种型IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab95819 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 5µl for 106 cells. ab35774-Rat monoclonal IgM, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
  • 组织特异性Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.
  • 序列相似性Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
  • 结构域Contains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 翻译后修饰Phosphorylated on tyrosine residues. Dephosphorylated by PTPN6.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD85 antigen-like family member D antibody
    • CD85d antibody
    • CD85d antigen antibody
    • ILT 4 antibody
    • ILT-4 antibody
    • ILT4 antibody
    • Immunoglobulin like transcript 4 antibody
    • Immunoglobulin-like transcript 4 antibody
    • Leukocyte immunoglobulin like receptor 2 antibody
    • Leukocyte immunoglobulin like receptor subfamily B member 2 antibody
    • Leukocyte immunoglobulin-like receptor 2 antibody
    • Leukocyte immunoglobulin-like receptor subfamily B member 2 antibody
    • Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 antibody
    • LILRA6 antibody
    • LILRB2 antibody
    • LIR 2 antibody
    • LIR-2 antibody
    • LIR2 antibody
    • LIRb antibody
    • LIRB2_HUMAN antibody
    • MIR 10 antibody
    • MIR-10 antibody
    • MIR10 antibody
    • Monocyte/macrophage immunoglobulin like receptor 10 antibody
    • Monocyte/macrophage immunoglobulin-like receptor 10 antibody
    see all

Anti-LILRB2 antibody [27D6] (FITC) 图像

  • Staining of normal Human peripheral blood cells with Rat IgM ? Isotype Control FITC (open histogram) or ab95819 (filled histogram). Cells in the monocyte gate were used for analysis.

Anti-LILRB2 antibody [27D6] (FITC) (ab95819)参考文献

ab95819 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"