Anti-LIGHT抗体(ab57901)

概述

  • 产品名称Anti-LIGHT抗体
    参阅全部 LIGHT 一抗
  • 描述
    小鼠单克隆抗体to LIGHT
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 61-170 of Human LIGHT

性能

应用

Our Abpromise guarantee covers the use of ab57901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
    • 组织特异性Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
    • 序列相似性Belongs to the tumor necrosis factor family.
    • 翻译后修饰N-glycosylated.
      The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
    • 细胞定位Cytoplasm; Secreted and Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 258 antibody
      • CD258 antibody
      • CD258 antigen antibody
      • Delta transmembrane LIGHT antibody
      • Herpes virus entry mediator ligand antibody
      • Herpesvirus entry mediator A antibody
      • Herpesvirus entry mediator ligand antibody
      • herpesvirus entry mediator-ligand antibody
      • HVEM L antibody
      • HVEM-L antibody
      • HVEML antibody
      • Ligand for herpesvirus entry mediator antibody
      • LIGHT antibody
      • LTg antibody
      • soluble form antibody
      • TNF14 antibody
      • TNF14_HUMAN antibody
      • TNFSF 14 antibody
      • Tnfsf14 antibody
      • TNFSF14 protein antibody
      • TR 2 antibody
      • TR2 antibody
      • Tumor necrosis factor (ligand) superfamily, member 14 antibody
      • Tumor necrosis factor ligand superfamily member 14 antibody
      • Tumor necrosis factor ligand superfamily, member 14 antibody
      • Tumor necrosis factor receptor like 2 antibody
      • tumor necrosis factor receptor-like 2 antibody
      • Tumor necrosis factor superfamily member 14 antibody
      • Tumor necrosis factor superfamily member LIGHT antibody
      see all

    Anti-LIGHT antibody 图像

    • LIGHT antibody (ab57901) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human spleen.
    • Western blot against tagged recombinant protein immunogen using ab57901 LIGHT antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-LIGHT antibody (ab57901)参考文献

    ab57901 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you very much for your call today and for letting us know about the trouble with ab57901.

    As we discussed, I'm sending a free of charge vial of ab90133 on the order ***, which should arrive late next week. Please keep me updated about t...

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    I now have more information to share with you in regards to how the anti-LIGHT antibody (ab57901) was used in order to obtain the stainingpresented on the datasheet of this produc...

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    Thank you for contacting us.

    I am unfamiliar with the Ventana LIGHT product and was unable tro locate a reference to it on their website. We do however offer 5 antibodies against LIGHT. Three are Rabbit IgG polyclonals, the other two are prod...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"