RabMAb

Anti-LI Cadherin抗体[EPR3997] (ab109220)

概述

  • 产品名称Anti-LI Cadherin抗体[EPR3997]
    参阅全部 LI Cadherin 一抗
  • 描述
    兔单克隆抗体[EPR3997] to LI Cadherin
  • 经测试应用适用于: WB, IP, IHC-Pmore details
    不适用于: Flow Cyt or ICC
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to the C terminus of Human LI Cadherin.

  • 阳性对照
    • WB: Human small intestine and colon cancer lysates IHC-P: Human colon and colonic adenocarcinoma tissues
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EPR3997
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab109220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 120 kDa (predicted molecular weight: 92 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Antigen retrieval is recommended.
  • 应用说明Is unsuitable for Flow Cyt or ICC.
  • 靶标

    • 功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.
    • 组织特异性Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin.
    • 序列相似性Contains 7 cadherin domains.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BILL-cadherin antibody
      • CAD17_HUMAN antibody
      • Cadherin 16 antibody
      • Cadherin 16, formerly antibody
      • Cadherin 17 antibody
      • cadherin 17, LI cadherin (liver-intestine) antibody
      • cadherin, liver-intestine antibody
      • Cadherin-17 antibody
      • CDH16 antibody
      • CDH16, formerly antibody
      • Cdh17 antibody
      • FLJ26931 antibody
      • Formerly Cadherin 16 antibody
      • Formerly CDH16 antibody
      • HPT 1 antibody
      • HPT-1 cadherin antibody
      • human intestinal peptide-associated transporter HPT-1 antibody
      • human peptide transporter 1 antibody
      • Intestinal peptide-associated transporter HPT 1 antibody
      • Intestinal peptide-associated transporter HPT-1 antibody
      • LI-cadherin antibody
      • Liver Cadherin antibody
      • liver intestine cadherin antibody
      • Liver-intestine cadherin antibody
      see all

    Anti-LI Cadherin antibody [EPR3997] 图像

    • All lanes : Anti-LI Cadherin antibody [EPR3997] (ab109220) at 1/1000 dilution

      Lane 1 : Human small intestine cancer lysates
      Lane 2 : Colon cancer lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 92 kDa
      Observed band size : 120 kDa (why is the actual band size different from the predicted?)
    • ab109220, at a 1/250 dilution, staining LI Cadherin in paraffin embedded Human colonic adenocarcinoma tissue by Immunohistochemistry.
    • ab109220, at a 1/250 dilution, staining LI Cadherin in paraffin embedded Human colon tissue by Immunohistochemistry.
    • ab109220 showing negative staining in Normal liver tissue.

    • ab109220 showing positive staining in Normal colon tissue.

    • ab109220 showing negative staining in Normal tonsil tissue.

    • ab109220 showing negative staining in Papillary carcinoma of thyroid gland tissue.

    • ab109220 showing negative staining in Normal kidney tissue.

    • ab109220 showing negative staining in Normal brain tissue.

    • ab109220 showing negative staining in Prostatic carcinoma tissue.

    • ab109220 showing negative staining in Breast carcinoma tissue.

    Anti-LI Cadherin antibody [EPR3997] (ab109220)参考文献

    ab109220 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab109220.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"