Anti-LFA3抗体[HI58a] (CF405M) (ab117738)

概述

  • 产品名称Anti-LFA3抗体[HI58a] (CF405M)
    参阅全部 LFA3 一抗
  • 描述
    小鼠单克隆抗体[HI58a] to LFA3 (CF405M)
  • 偶联物CF405M. Ex: 408nm, Em: 452nm
  • 特异性ab117738 is recommended for use in flow cytometry for identification of erythrocytes, platelets, monocytes, bone marrow cells, a lymphocyte subset and epithelial and endothelial cells.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Peripheral Blood Mononuclear Cell

  • 阳性对照
    • Normal Human peripheral blood cells
  • 常规说明


    ab117738 recognizes the Human CD58 cell surface antigen. CD58 is a cell adhesion molecule, which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium, and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria

    CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液pH: 7.20
    Preservative: 0.09% Sodium azide
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • Primary antibody说明ab117738 recognizes the Human CD58 cell surface antigen. CD58 is a cell adhesion molecule, which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium, and endothelial cells. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on haemopoietic cells in individuals with paroxysmal nocturnal haemoglobinuria
  • 克隆单克隆
  • 克隆编号HI58a
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab117738 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 5µl for 106 cells. ab126026-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
  • 序列相似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AG3 antibody
    • CD58 antibody
    • CD58 antigen (lymphocyte function associated antigen 3)1 antibody
    • CD58 antigen antibody
    • CD58 antigen, (lymphocyte function associated antigen 3) antibody
    • CD58 molecule antibody
    • FLJ23181 antibody
    • FLJ43722 antibody
    • LFA 3 antibody
    • LFA-3 antibody
    • LFA3 antibody
    • LFA3_HUMAN antibody
    • Lymphocyte Function Associated Antigen Type 3 antibody
    • Lymphocyte function-associated antigen 3 antibody
    • Surface glycoprotein LFA 3 antibody
    • Surface glycoprotein LFA-3 antibody
    see all

Anti-LFA3 antibody [HI58a] (CF405M) 图像

  • Staining of normal Human peripheral blood cells with ab117738. Cells in the Lymphocytes gate were used for analysis (red histogram).

Anti-LFA3 antibody [HI58a] (CF405M) (ab117738)参考文献

ab117738 has not yet been referenced specifically in any publications.

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