Anti-Leucyl-cystinyl aminopeptidase抗体(ab107450)

概述

  • 产品名称Anti-Leucyl-cystinyl aminopeptidase抗体
    参阅全部 Leucyl-cystinyl aminopeptidase 一抗
  • 描述
    兔多克隆抗体to Leucyl-cystinyl aminopeptidase
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide between N terminal amino acids 16-46 of Human Leucyl-cystinyl aminopeptidase (NP_005566.2 , NP_787116.2), conjugated to KLH.

  • 阳性对照
    • HL60 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab107450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 117 kDa.

靶标

  • 功能Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
  • 组织特异性Highly expressed in placenta, heart, kidney and small intestine. Detected at lower levels in neuronal cells in the brain, in skeletal muscle, spleen, liver, testes and colon.
  • 序列相似性Belongs to the peptidase M1 family.
  • 翻译后修饰The pregnancy serum form is derived from the membrane-bound form by proteolytic processing.
    N-glycosylated.
  • 细胞定位Cell membrane. In brain only the membrane-bound form is found. The protein resides in intracellular vesicles together with GLUT4 and can then translocate to the cell surface in response to insulin and/or oxytocin. Localization may be determined by dileucine internalization motifs, and/or by interaction with tankyrases and Secreted. During pregnancy serum levels are low in the first trimester, rise progressively during the second and third trimester and decrease rapidly after parturition.
  • Information by UniProt
  • 数据库链接
  • 别名
    • angiotensin IV receptor antibody
    • AT (4) receptor antibody
    • CAP antibody
    • Cystinyl aminopeptidase antibody
    • insulin regulated aminopeptidase antibody
    • insulin regulated membrane aminopeptidase antibody
    • insulin responsive aminopeptidase antibody
    • Insulin-regulated membrane aminopeptidase antibody
    • Insulin-responsive aminopeptidase antibody
    • IRAP antibody
    • LCAP_HUMAN antibody
    • Leucyl-cystinyl aminopeptidase antibody
    • LNPEP antibody
    • OTase antibody
    • Oxytocinase antibody
    • P-LAP antibody
    • Placental leucine aminopeptidase antibody
    • PLAP antibody
    • pregnancy serum form antibody
    • vasopressinase antibody
    see all

Anti-Leucyl-cystinyl aminopeptidase antibody 图像

  • Anti-Leucyl-cystinyl aminopeptidase antibody (ab107450) at 1/100 dilution + HL60 cell lysate at 35 µg

    Predicted band size : 117 kDa

Anti-Leucyl-cystinyl aminopeptidase antibody (ab107450)参考文献

ab107450 has not yet been referenced specifically in any publications.

Product Wall

I have asked our commercial team to add the blocking peptide to ab107450. This can now be purchased under reference number ab185019.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"