概述

  • 产品名称Anti-Leptin抗体
    参阅全部 Leptin 一抗
  • 描述
    兔多克隆抗体to Leptin
  • 特异性The antibody will recognize recombinant and native 16 kDa leptin from mouse. Reactivity with leptin from other sources is unknown.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant mouse leptin 16,000 MW produced in E. coli.

性能

应用

Our Abpromise guarantee covers the use of ab2095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA (suggested working dilution 1:2,400) and immunoblotting (suggested working dilution 1:200 to 1:400). Reactivity in other immunoassays is unknown. Optimal titers for other applications should be determined by the researcher.
  • 靶标

    • 功能May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
    • 疾病相关Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
    • 序列相似性Belongs to the leptin family.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ94114 antibody
      • LEP antibody
      • LEP_HUMAN antibody
      • LEPD antibody
      • Leptin (murine obesity homolog) antibody
      • Leptin (obesity homolog, mouse) antibody
      • Leptin antibody
      • Leptin Murine Obesity Homolog antibody
      • Leptin Precursor Obesity Factor antibody
      • OB antibody
      • Obese protein antibody
      • Obese, mouse, homolog of antibody
      • Obesity antibody
      • Obesity factor antibody
      • Obesity homolog mouse antibody
      • Obesity Murine Homolog Leptin antibody
      • OBS antibody
      • OTTHUMP00000212285 antibody
      see all

    Anti-Leptin antibody (ab2095)参考文献

    This product has been referenced in:
    • Krishnapuram R  et al. Template to improve glycemic control without reducing adiposity or dietary fat. Am J Physiol Endocrinol Metab 300:E779-89 (2011). WB ; Mouse . Read more (PubMed: 21266671) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"