概述

  • 产品名称Anti-LEPREL1抗体
    参阅全部 LEPREL1 一抗
  • 描述
    兔多克隆抗体to LEPREL1
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    internal sequence amino acids 307-447 of Human LEPREL1.

  • 阳性对照
    • Human skeletal muscle tissue. RT4 and U-251 MG cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab121270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 功能Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V.
  • 组织特异性Expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells.
  • 序列相似性Belongs to the leprecan family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 4 TPR repeats.
  • 细胞定位Endoplasmic reticulum. Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4832416N06 antibody
    • AW553532 antibody
    • Leprecan like 1 antibody
    • Leprecan-like protein 1 antibody
    • Leprel1 antibody
    • MCVD antibody
    • MLAT4 antibody
    • Myxoid liposarcoma-associated protein 4 antibody
    • P3H2 antibody
    • P3H2_HUMAN antibody
    • Prolyl 3 hydroxylase 3 antibody
    • Prolyl 3-hydroxylase 2 antibody
    see all

Anti-LEPREL1 antibody 图像

  • ab121270 at 1/25 dilution staining LEPREL1 in paraffin-embedded Human skeletal muscle by Immunohistochemistry.
  • All lanes : Anti-LEPREL1 antibody (ab121270) at 1/250 dilution

    Lane 1 : Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11
    Lane 2 : RT-4 Cell lysate.
    Lane 3 : U-251 MG Cell lysate.
    Lane 4 : Human Plasma
    Lane 5 : Human Liver lysate.
    Lane 6 : Human Tonsil lysate.

    Developed using the ECL technique

Anti-LEPREL1 antibody (ab121270)参考文献

ab121270 has not yet been referenced specifically in any publications.

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