概述

  • 产品名称
    Anti-LEPREL1抗体
    参阅全部 LEPREL1 一抗
  • 描述
    兔多克隆抗体to LEPREL1
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    internal sequence amino acids 307-447 of Human LEPREL1.

  • 阳性对照
    • Human skeletal muscle tissue. RT4 and U-251 MG cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab121270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500. Predicted molecular weight: 81 kDa.

靶标

  • 功能
    Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V.
  • 组织特异性
    Expressed in heart, placenta, lung, liver, skeletal muscle and kidney. Expression localized to the epithelia of bile ducts and to the sacroplasm of heart muscle and skeletal muscle. In the pancreas, localized to a subpopulation of Langerhans islet cells and in the salivary gland, expressed in acinar cells.
  • 序列相似性
    Belongs to the leprecan family.
    Contains 1 Fe2OG dioxygenase domain.
    Contains 4 TPR repeats.
  • 细胞定位
    Endoplasmic reticulum. Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4832416N06 antibody
    • AW553532 antibody
    • Leprecan like 1 antibody
    • Leprecan-like protein 1 antibody
    • Leprel1 antibody
    • MCVD antibody
    • MLAT4 antibody
    • Myxoid liposarcoma-associated protein 4 antibody
    • P3H2 antibody
    • P3H2_HUMAN antibody
    • Prolyl 3 hydroxylase 3 antibody
    • Prolyl 3-hydroxylase 2 antibody
    see all

图片

  • Anti-LEPREL1 antibody (ab121270) + Human cell line A-431 cell lysates.

    Predicted band size : 81 kDa
  • ab121270 at 1/25 dilution staining LEPREL1 in paraffin-embedded Human skeletal muscle by Immunohistochemistry.
  • All lanes : Anti-LEPREL1 antibody (ab121270)

    Lane 1 : Mouse cell line NIH-3T3
    Lane 2 : Rat cell line NBT-II


    Predicted band size : 81 kDa

文献

ab121270 has not yet been referenced specifically in any publications.

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