Anti-LEFTY2抗体(ab88088)

概述

  • 产品名称Anti-LEFTY2抗体
    参阅全部 LEFTY2 一抗
  • 描述
    小鼠单克隆抗体to LEFTY2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 77-180 of human LEFTY2 protein (NP_003231) with a proprietary tag.

  • 阳性对照
    • Human skeletal muscle tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab88088 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 41 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding.
  • 组织特异性Mesenchymal cells of the endometrial stroma.
  • 疾病相关Defects in LEFTY2 are the cause of left-right axis malformations (LRAM) [MIM:601877]. The defect includes left pulmonary isomerism, with cardiac anomalies characterized by complete atrioventricular canal defect and hypoplastic left ventricle, and interrupted inferior vena cava.
  • 序列相似性Belongs to the TGF-beta family.
  • 发展阶段Transiently expressed before and during menstrual bleeding.
  • 翻译后修饰The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EBAF antibody
    • Endometrial bleeding associated factor (left right determination factor A transforming growth factor beta superfamily) antibody
    • Endometrial bleeding associated factor antibody
    • Endometrial bleeding-associated factor antibody
    • Left right determination factor 2 antibody
    • Left right determination factor A antibody
    • Left-right determination factor 2 antibody
    • Left-right determination factor A antibody
    • LEFTA antibody
    • LEFTY 2 antibody
    • LEFTY2 antibody
    • LEFTYA antibody
    • LFTY2 transforming growth factor, beta -4 antibody
    • LFTY2, mouse, homolog of antibody
    • LFTY2_HUMAN antibody
    • MGC46222 antibody
    • Protein lefty 2 antibody
    • Protein lefty A antibody
    • Protein lefty-2 antibody
    • Protein lefty-A antibody
    • Protein lefty2 antibody
    • PSEC0024 antibody
    • TGF beta 4 antibody
    • TGF-beta-4 antibody
    • TGFB4 antibody
    • Transforming growth factor beta 4 antibody
    • Transforming growth factor beta-4 antibody
    see all

Anti-LEFTY2 antibody 图像

  • Anti-LEFTY2 antibody (ab88088) at 5 µg/ml + human skeletal muscle lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 41 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)

Anti-LEFTY2 antibody (ab88088)参考文献

ab88088 has not yet been referenced specifically in any publications.

Product Wall

Vielen Dank für Ihre Anfrage.

Da die beiden Proteine sehr homolog sind und das Immunogen im Speziellen eine Homologie von 98% aufweist, gehen wir davon aus, dass LEFTY1 von ab88088 auch erkannt wird.

Dies wurde jedoch nicht exp...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"