概述
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产品名称Anti-LECT1抗体- Carboxyterminal end
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描述兔多克隆抗体to LECT1 - Carboxyterminal end
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宿主Rabbit
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经测试应用适用于: IHC-P, ELISA, WBmore details
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种属反应性与反应: Human
预测可用于: Mouse, Rabbit
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免疫原
KLH conjugated synthetic peptide selected from the C-terminal region of human LECT1.
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阳性对照
- NCI-H460 membrane lysate
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.09% Sodium Azide
Constituents: PBS -
Concentration information loading... -
纯度Ammonium Sulphate Precipitation
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纯化说明Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab71450 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-P | 1/10 - 1/50. | |
| ELISA | 1/1000. | |
| WB | 1/50 - 1/100. Detects a band of approximately 37 kDa. |
靶标
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功能Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
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组织特异性Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
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序列相似性Belongs to the chondromodulin-1 family.
Contains 1 BRICHOS domain. -
发展阶段Expressed at 9 weeks in developing cartilagenous bone rudiments.
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翻译后修饰After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
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细胞定位Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
- Information by UniProt
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数据库链接
- Entrez Gene: 11061 Human
- Entrez Gene: 16840 Mouse
- Omim: 605147 Human
- SwissProt: O75829 Human
- SwissProt: Q9Z1F6 Mouse
- Unigene: 421391 Human
- Unigene: 46561 Mouse
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别名
- BRICD3 antibody
- BRICHOS domain containing 3 antibody
- CH-SP antibody
see all
图片
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Western blot - LECT1 antibody (ab71450)Anti-LECT1 antibody - Carboxyterminal end (ab71450) at 1/60 dilution + NCI-H460 cell line lysates at 12.5 µg
Observed band size: 37 kDa (why is the actual band size different from the predicted?) -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LECT1 antibody - Carboxyterminal end (ab71450)Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
文献
ab71450 has not yet been referenced specifically in any publications.
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"