Anti-LECT1抗体- Carboxyterminal end (ab71450)

概述

  • 产品名称Anti-LECT1抗体- Carboxyterminal end
    参阅全部 LECT1 一抗
  • 描述
    兔多克隆抗体to LECT1 - Carboxyterminal end
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of human LECT1.

  • 阳性对照
    • NCI-H460 membrane lysate

性能

应用

Our Abpromise guarantee covers the use of ab71450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/10 - 1/50.
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 37 kDa.

靶标

  • 功能Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
  • 组织特异性Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.
  • 序列相似性Belongs to the chondromodulin-1 family.
    Contains 1 BRICHOS domain.
  • 发展阶段Expressed at 9 weeks in developing cartilagenous bone rudiments.
  • 翻译后修饰After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
  • 细胞定位Endomembrane system and Secreted. Accumulated in the inter-territorial matrix of cartilage.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BRICD3 antibody
    • BRICHOS domain containing 3 antibody
    • CH-SP antibody
    • CHM I antibody
    • ChM-I antibody
    • CHM1 antibody
    • chondromodulin antibody
    • Chondromodulin I antibody
    • Chondromodulin-1 antibody
    • Chondromodulin-I antibody
    • Chondrosurfactant protein antibody
    • LECT 1 antibody
    • Lect1 antibody
    • LECT1_HUMAN antibody
    • Leukocyte cell derived chemotaxin 1 antibody
    • Multiple myeloma tumor suppressor 1 antibody
    • MYETS1 antibody
    see all

Anti-LECT1 antibody - Carboxyterminal end 图像

  • Anti-LECT1 antibody - Carboxyterminal end (ab71450) at 1/60 dilution + NCI-H460 cell line lysates at 12.5 µg

    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-LECT1 antibody - Carboxyterminal end (ab71450)参考文献

ab71450 has not yet been referenced specifically in any publications.

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