Anti-LDL (Copper oxidized)抗体(ab14519)

概述

  • 产品名称
    Anti-LDL (Copper oxidized)抗体
  • 描述
    兔多克隆抗体to LDL (Copper oxidized)
  • 经测试应用
    适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human Cu2+ oxidised LDL.

应用

Our Abpromise guarantee covers the use of ab14519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
IHC-P
  • 应用说明
    ELISA: 1/500 - 1/5000.
    IHC-P: <1/500.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      When too much LDL cholesterol circulates in the blood, it can slowly build up in the inner walls of the arteries that feed the heart and brain. Together with other substances it can form plaque, a thick, hard deposit that can clog those arteries. This condition is known as atherosclerosis. Oxidized lipoproteins are formed by free radical damage to lipids that accumulate in macrophages and smooth muscle cells causing foam cell formation, an initial step in the disease.
    • 细胞定位
      Secreted (probable)

    文献

    This product has been referenced in:
    • Li R  et al. Role of liver sinusoidal endothelial cells and stabilins in elimination of oxidized low-density lipoproteins. Am J Physiol Gastrointest Liver Physiol 300:G71-81 (2011). Read more (PubMed: 21030611) »
    • Dong Y  et al. Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo. Diabetes 59:1386-96 (2010). ICC/IF ; Mouse . Read more (PubMed: 20299472) »

    See all 5 Publications for this product

    客户评价及客户问答

    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Sample
    Rat Tissue sections (Lung)
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: Citrate buffer PH6.0
    Permeabilization
    No
    Specification
    Lung
    Blocking step
    Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Fixative
    Paraformaldehyde
    Username

    Abcam user community

    Verified customer

    提交于 Aug 09 2015

    Thank you for your enquiry. ab14519 is the only anti-LDL "Copper oxidised" antiserum that we stock. Please can you tell me whether your customer is interested in the oxidised form of the protein or the native equivalent as our antisera carry this s...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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