概述

  • 产品名称Anti-LDB1抗体
    参阅全部 LDB1 一抗
  • 描述
    兔多克隆抗体to LDB1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog, Pig, Zebrafish
  • 免疫原

    A region within synthetic peptide: EPTRQQPSKR RKRKMSGGST MSSGGGNTNN SNSKKKSPAS TFALSSQVPD, corresponding to amino acids 251-300 of Human LDB1

  • 阳性对照
    • Jurkat cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab48573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1.5625e+006.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 47 kDa (predicted molecular weight: 42 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
  • 组织特异性Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • 序列相似性Belongs to the LDB family.
  • 结构域The dimerization domain is located in the N-terminus.
  • 翻译后修饰Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Carboxyl Terminal LIM Domain Binding 2 antibody
    • Carboxyl-terminal LIM domain-binding protein 2 antibody
    • CLIM 2 antibody
    • CLIM-2 antibody
    • hLdb1 antibody
    • LDB-1 antibody
    • ldb1 antibody
    • LDB1_HUMAN antibody
    • LIM Domain Binding 1 antibody
    • LIM domain binding factor CLIM2 antibody
    • LIM domain-binding factor CLIM2 antibody
    • LIM domain-binding protein 1 antibody
    • NLI antibody
    • Nuclear LIM Domain Interactor antibody
    • Nuclear LIM interactor antibody
    • xldb1 antibody
    see all

Anti-LDB1 antibody 图像

  • Anti-LDB1 antibody (ab48573) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 42 kDa
    Observed band size : 47 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

Anti-LDB1 antibody (ab48573)参考文献

ab48573 has not yet been referenced specifically in any publications.

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