概述

  • 产品名称Anti-LCMT2抗体
    参阅全部 LCMT2 一抗
  • 描述
    兔多克隆抗体to LCMT2
  • 特异性ab112562 is predicted to not cross-react with other LCMT protein family members. At least two isoforms of LCMT2 are known to exist; this antibody will detect only the long isoform.
  • 经测试应用适用于: WB, ICC/IF, ICC, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (16 amino acids) near the N terminal of Human LCMT2.

  • 阳性对照
    • Rat brain tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab112562 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 76 kDa.
ICC/IF Use a concentration of 20 µg/ml.
ICC Use a concentration of 5 µg/ml.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.
  • 通路tRNA modification; wybutosine-tRNA(Phe) biosynthesis.
  • 序列相似性Belongs to the methyltransferase superfamily. LCMT family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA0547 antibody
    • LCMT 2 antibody
    • Lcmt2 antibody
    • LCMT2_HUMAN antibody
    • Leucine carboxyl methyltransferase 2 antibody
    • MGC9534 antibody
    • p21WAF1/CIP1 promoter interacting protein antibody
    • p21WAF1/CIP1 promoter-interacting protein antibody
    • PPM2 antibody
    • tRNA Wybutosine synthesizing protein 4 antibody
    • tRNA wybutosine synthesizing protein 4 homolog antibody
    • tRNA wybutosine-synthesizing protein 4 homolog antibody
    • tRNA yW synthesizing protein 4 antibody
    • tRNA yW synthesizing protein 4 homolog antibody
    • tRNA yW-synthesizing protein 4 homolog antibody
    • TYW4 antibody
    see all

Anti-LCMT2 antibody 图像

  • Immunofluorescence of LCMT2 in mouse brain tissue with ab112562 at 20 ug/mL.
  • All lanes : Anti-LCMT2 antibody (ab112562) at 1 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat brain tissue lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 76 kDa
  • Immunohistochemistry of LCMT2 in mouse brain tissue with ab112562 at 5 ug/mL.

Anti-LCMT2 antibody (ab112562)参考文献

ab112562 has not yet been referenced specifically in any publications.

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