Anti-LC3C抗体- N-terminal (ab229667)

概述

  • 产品名称
    Anti-LC3C抗体- N-terminal
    参阅全部 LC3C 一抗
  • 描述
    兔多克隆抗体to LC3C - N-terminal
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide within Human LC3C (N terminal). The exact sequence is proprietary. Carrier-protein conjugated
    Database link: Q9BXW4

  • 阳性对照
    • U-87MG, SK-N-SH, IMR32 and SK-N-AS whole cell extracts

应用

Our Abpromise guarantee covers the use of ab229667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 17 kDa.

靶标

  • 功能
    Probably involved in formation of autophagosomal vacuoles (autophagosomes).
  • 组织特异性
    Most abundant in placenta, lung and ovary.
  • 序列相似性
    Belongs to the MAP1 LC3 family.
  • 翻译后修饰
    The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
  • 细胞定位
    Cytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATG8J antibody
    • Autophagy-related protein LC3 C antibody
    • Autophagy-related ubiquitin-like modifier LC3 C antibody
    • LC3 like protein 2 antibody
    • MAP1 light chain 3 like protein 2 antibody
    • MAP1 light chain 3 like protein 3 antibody
    • MAP1 light chain 3-like protein 3 antibody
    • MAP1A/MAP1B LC3 C antibody
    • MAP1A/MAP1B light chain 3 C antibody
    • MAP1LC3C antibody
    • Microtubule-associated protein 1 light chain 3 gamma antibody
    • Microtubule-associated proteins 1A/1B light chain 3C antibody
    • MLP3C_HUMAN antibody
    see all

图片

  • All lanes : Anti-LC3C antibody - N-terminal (ab229667) at 1/1000 dilution

    Lane 1 : U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell extract
    Lane 2 : SK-N-SH (human neuroblastoma cell line) whole cell extract
    Lane 3 : IMR32 (Human brain neuroblast cell line) whole cell extract
    Lane 4 : SK-N-AS (human neuroblastoma cell line) whole cell extract

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 17 kDa

    15% SDS-PAGE gel.

文献

ab229667 has not yet been referenced specifically in any publications.

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