Anti-LC3C抗体- C-terminal (ab191574)

概述

  • 产品名称
    Anti-LC3C抗体- C-terminal
    参阅全部 LC3C 一抗
  • 描述
    兔多克隆抗体to LC3C - C-terminal
  • 宿主
    Rabbit
  • 特异性
    ab191574 is predicted to not cross-react with LC3A or LC3B.
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human LC3C (C terminal). (18 amino acid peptide from near the carboxy terminus; NP_001004343).
    Database link: Q9BXW4

  • 阳性对照
    • Human brain tissue lysate; Human brain tissue.

应用

Our Abpromise guarantee covers the use of ab191574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 17 kDa).
IHC-P Use a concentration of 5 - 20 µg/ml.

靶标

  • 功能
    Probably involved in formation of autophagosomal vacuoles (autophagosomes).
  • 组织特异性
    Most abundant in placenta, lung and ovary.
  • 序列相似性
    Belongs to the MAP1 LC3 family.
  • 翻译后修饰
    The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
  • 细胞定位
    Cytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATG8J antibody
    • Autophagy-related protein LC3 C antibody
    • Autophagy-related ubiquitin-like modifier LC3 C antibody
    • LC3 like protein 2 antibody
    • MAP1 light chain 3 like protein 2 antibody
    • MAP1 light chain 3 like protein 3 antibody
    • MAP1 light chain 3-like protein 3 antibody
    • MAP1A/MAP1B LC3 C antibody
    • MAP1A/MAP1B light chain 3 C antibody
    • MAP1LC3C antibody
    • Microtubule-associated protein 1 light chain 3 gamma antibody
    • Microtubule-associated proteins 1A/1B light chain 3C antibody
    • MLP3C_HUMAN antibody
    see all

图片

  • All lanes : Anti-LC3C antibody - C-terminal (ab191574) at 1 µg/ml

    Lane 1 : Human brain tissue lysate
    Lane 2 : Human brain tissue lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 17 kDa
    Observed band size: 16 kDa (why is the actual band size different from the predicted?)

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling LC3C with ab191574 at 5 µg/ml.

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling LC3C with ab191574 at 20 µg/ml.

文献

ab191574 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab191574.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册