Anti-LC3C抗体(ab118501)

概述

  • 产品名称Anti-LC3C抗体
    参阅全部 LC3C 一抗
  • 描述
    山羊多克隆抗体to LC3C
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rhesus monkey, Marmoset (common)
  • 免疫原

    Synthetic peptide:

    SQETFGCLESAAPRD

    , corresponding to amino acids 121-135 of Human LC3C (NP_001004343.1).

  • 阳性对照
    • Human Cerebellum, Human Kidney

应用

Our Abpromise guarantee covers the use of ab118501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 3.75 - 7.5 µg/ml.

靶标

  • 功能Probably involved in formation of autophagosomal vacuoles (autophagosomes).
  • 组织特异性Most abundant in placenta, lung and ovary.
  • 序列相似性Belongs to the MAP1 LC3 family.
  • 翻译后修饰The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
  • 细胞定位Cytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATG8J antibody
    • Autophagy-related protein LC3 C antibody
    • Autophagy-related ubiquitin-like modifier LC3 C antibody
    • LC3 like protein 2 antibody
    • MAP1 light chain 3 like protein 2 antibody
    • MAP1 light chain 3 like protein 3 antibody
    • MAP1 light chain 3-like protein 3 antibody
    • MAP1A/MAP1B LC3 C antibody
    • MAP1A/MAP1B light chain 3 C antibody
    • MAP1LC3C antibody
    • Microtubule-associated protein 1 light chain 3 gamma antibody
    • Microtubule-associated proteins 1A/1B light chain 3C antibody
    • MLP3C_HUMAN antibody
    see all

Anti-LC3C antibody 图像

  • ab118501 at 3.75 µg/ml staining LC3C in Human Cerebellum by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • ab118501 at 3.75 µg/ml staining LC3C in Human Kidney by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-LC3C antibody (ab118501)参考文献

ab118501 has not yet been referenced specifically in any publications.

Product Wall

As stated on the datasheet, the immunogen of ab118501 is a synthetic peptide:
SQETFGCLESAAPRD , corresponding to amino acids 121-135 of Human LC3C (NP_001004343.1).

This sequence shows no homology LC3A isoform 1 and 2 and LC3B so therefo...

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Thank you for contacting us.
At this time, no cross-reactivity testing has been done for these products, although the immunogens show low homology with these proteins.

I hope this information is helpful to you. Please do not hesitate to...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"