概述

  • 产品名称Anti-Laminin gamma 1抗体
    参阅全部 Laminin gamma 1 一抗
  • 描述
    兔多克隆抗体to Laminin gamma 1
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Drosophila melanogaster
  • 免疫原

    Full length native protein (purified) (Fruit fly (Drosophila melanogaster))

性能

应用

Our Abpromise guarantee covers the use of ab47651 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 182 kDa.
ICC/IF 1/500.

靶标

  • 功能Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
  • 组织特异性Found in the basement membranes (major component).
  • 序列相似性Contains 11 laminin EGF-like domains.
    Contains 1 laminin IV type A domain.
    Contains 1 laminin N-terminal domain.
  • 结构域The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
    Domains VI and IV are globular.
  • 细胞定位Secreted > extracellular space > extracellular matrix > basement membrane.
  • Information by UniProt
  • 数据库链接
    • 别名
      • LAMB2 antibody
      • lamc1 antibody
      • LAMC1_HUMAN antibody
      • Laminin B2 chain antibody
      • Laminin subunit gamma-1 antibody
      • Laminin, gamma 1 (formerly LAMB2) antibody
      • Laminin-1 subunit gamma antibody
      • Laminin-10 subunit gamma antibody
      • Laminin-11 subunit gamma antibody
      • Laminin-2 subunit gamma antibody
      • Laminin-3 subunit gamma antibody
      • Laminin-4 subunit gamma antibody
      • Laminin-6 subunit gamma antibody
      • Laminin-7 subunit gamma antibody
      • Laminin-8 subunit gamma antibody
      • Laminin-9 subunit gamma antibody
      • MGC87297 antibody
      • S-LAM gamma antibody
      • S-laminin subunit gamma antibody
      see all

    Anti-Laminin gamma 1 antibody (ab47651)参考文献

    This product has been referenced in:
    • Schleede J & Blair SS The Gyc76C Receptor Guanylyl Cyclase and the Foraging cGMP-Dependent Kinase Regulate Extracellular Matrix Organization and BMP Signaling in the Developing Wing of Drosophila melanogaster. PLoS Genet 11:e1005576 (2015). IHC ; Drosophila melanogaster . Read more (PubMed: 26440503) »
    • Dekanty A  et al. Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia. Proc Natl Acad Sci U S A 109:20549-54 (2012). ICC/IF ; Drosophila melanogaster . Read more (PubMed: 23184991) »

    See all 4 Publications for this product

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