Anti-Lambda Light chain抗体(FITC) (ab9006)

概述

  • 产品名称Anti-Lambda Light chain抗体(FITC)
    参阅全部 Lambda Light chain 一抗
  • 描述
    羊多克隆抗体to Lambda Light chain (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性The unconjugated immunoglobulin gives a single arc when tested by immunoelectrophoresis against human serum. Identity has been confirmed by double diffusion (Ouchterlony) against human serum and an anti-human lambda of known specificity.
  • 经测试应用适用于: IHC-Fr, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    The immunogen used was human lambda-chain purified from disease state urines and shown to be homogeneous by SDS-PAGE.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液PBS pH 7.2, 0.1% BSA and 0.01% sodium azide
  • Concentration information loading...
  • 纯度IgG fraction
  • 克隆多克隆
  • 同种型IgG
  • 轻链类型unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab9006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
ICC/IF
  • 应用说明Immunofluorescence: Direct on frozen sections of human tonsil: 1/20 – 1/40

    Working dilutions of theconjugate must be made in a suitable buffer (e.g. 0.15M phosphate buffered saline, pH7.2) and should be prepared immediately prior touse.
    Optimal dilutions should be determined by the individual laboratory.
  • 靶标

    • 相关性All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
    • 细胞定位Cytoplasmic
    • 数据库链接
    • 别名
      • Bence Jones protein antibody
      • BJP antibody
      • Constant region of lambda light chains antibody
      • Ig lambda chain C regions antibody
      • ig lambda-6 chain C region antibody
      • IGLC 1 antibody
      • IGLC 2 antibody
      • IGLC 3 antibody
      • IGLC antibody
      • IGLC1 antibody
      • IGLC2 antibody
      • IGLC3 antibody
      • IGLC6 antibody
      • IGLV antibody
      • Immunoglobulin lambda constant 1 antibody
      • Immunoglobulin lambda constant regin 1 antibody
      • immunoglobulin lambda gene cluster antibody
      • Immunoglobulin lambda locus antibody
      • Immunoglobulin lambda variable cluster antibody
      • Immunoglobulin: lambda light chain antibody
      • Mcg marker antibody
      • Paraprotein antibody
      see all

    Anti-Lambda Light chain antibody (FITC) (ab9006)参考文献

    ab9006 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us.

    My colleague has confirmed that we do not currently OEM any of our products for resale. If you are interested in using our products to develop other assays such as kits, my colleagues at mailto:sales@abcam.com can...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"