概述

  • 产品名称Anti-Laeverin抗体
    参阅全部 Laeverin 一抗
  • 描述
    小鼠多克隆抗体to Laeverin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human Laeverin protein (AAH45809).

  • 阳性对照
    • Laeverin transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab72692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Predicted molecular weight (for isoform 4): 22 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.
    • 组织特异性Specifically expressed in placenta and not in other tissues. Mainly found at the cell surface region of the extravillous trophoblasts. Detected on extravillous trophoblasts in the outer layer of the chorion laeve in the fetal membrane Not detected on either fetal amnionic epithelial cells or maternal decidual cells. Also detected in the migrating extravillous trophoblasts in the maternal decidual tissues (at protein level).
    • 序列相似性Belongs to the peptidase M1 family.
    • 翻译后修饰N-glycosylated.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Aminopeptidase Q antibody
      • AMPQ_HUMAN antibody
      • AP-Q antibody
      • APQ antibody
      • Aqpep antibody
      • CHL2 antigen antibody
      • FLJ90650 antibody
      • Laeverin antibody
      • LVRN antibody
      • MGC125378 antibody
      • MGC125379 antibody
      • RGD1562779 antibody
      see all

    Anti-Laeverin antibody 图像

    • All lanes : Anti-Laeverin antibody (ab72692) at 1/500 dilution

      Lane 1 : Laeverin transfected 293T lysate
      Lane 2 : Non transfected 293T lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

      Predicted band size : 22 kDa
      Observed band size : 20 kDa (why is the actual band size different from the predicted?)

    Anti-Laeverin antibody (ab72692)参考文献

    ab72692 has not yet been referenced specifically in any publications.

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