Anti-La Crosse Virus G1 + La Crosse Virus G2抗体[10G5.4] (ab24298)

概述

  • 产品名称Anti-La Crosse Virus G1 + La Crosse Virus G2抗体[10G5.4]
  • 描述
    小鼠单克隆抗体[10G5.4] to La Crosse Virus G1 + La Crosse Virus G2
  • 特异性Recognizes G1 and G2; virus neutralizing.
  • 经测试应用适用于: ELISA, ICC/IF, IP, WB, Neutralisingmore details
  • 种属反应性
    Reacts with La Crosse Virus. Not yet tested in other species.
  • 免疫原

    La Crosse Virus (LACV) grown on E6 Vero cells and purified by sucrose gradient centrifugation.

性能

应用

Our Abpromise guarantee covers the use of ab24298 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.
IP Use at an assay dependent dilution.
WB Use at an assay dependent dilution.
Neutralising Use at an assay dependent dilution.

靶标

  • 相关性La Crosse virus is an etiologic agent for childhood encephalitis in North America. Structurally, the nucleocapsid of this virus is enclosed by a host-derived lipid envelope holding two virion glycoproteins, G1 and G2. These proteins are believed to be responsible for attachment of the virus to cells. Adsorption of La Crosse-Virus to cells in culture is mediated by surface glycoproteins G1 and G2. G1 has been shown to be important for infection in vertebrate hosts, but can be cleaved by the proteases found in the mosquito midgut. It was determined that G2 attaches to mosquito midgut cells and therefore may be the virus attachment protein in the mosquito.
  • 别名
    • LACV antibody

Anti-La Crosse Virus G1 + La Crosse Virus G2 antibody [10G5.4] (ab24298)参考文献

This product has been referenced in:
  • Cheng LL  et al. Identification and localization of conserved antigenic epitopes on the G2 proteins of California serogroup Bunyaviruses. Viral Immunol 13:201-13 (2000). Read more (PubMed: 10893000) »
  • Ludwig GV  et al. Monoclonal antibodies directed against the envelope glycoproteins of La Crosse virus. Microb Pathog 11:411-21 (1991). Read more (PubMed: 1795631) »

See all 2 Publications for this product

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Gracias por contactarnos.

Me temo que no se conoce reactividad cruzada con otras especies de la misma familia del virus.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"