概述

  • 产品名称Anti-L3MBTL2抗体
    参阅全部 L3MBTL2 一抗
  • 描述
    兔多克隆抗体to L3MBTL2
  • 经测试应用适用于: IHC-P, IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 655 and 705 of Human L3MBTL2 (NP_113676.2).

  • 阳性对照
    • HeLa whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab101272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1000 - 1/5000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
    • 序列相似性Contains 1 FCS-type zinc finger.
      Contains 4 MBT repeats.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 3bt like 2 protein antibody
      • 3bt like protein antibody
      • DKFZP761I141 antibody
      • H-l(3)mbt-like protein 2 antibody
      • H-l(3)mbt-like protein antibody
      • Hl antibody
      • Hl(3)mbt like protein antibody
      • Hl(3)mbtl antibody
      • L antibody
      • l(3)mbt like 2 (Drosophila) antibody
      • l(3)mbt like 2 antibody
      • L(3)mbt-like 2 protein antibody
      • L(3)mbt-like protein 2 antibody
      • L3MBTL2 antibody
      • Lethal antibody
      • Lethal(3)malignant brain tumor-like 2 protein antibody
      • Lethal(3)malignant brain tumor-like protein 2 antibody
      • LMBL2_HUMAN antibody
      see all

    Anti-L3MBTL2 antibody 图像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling L3MBTL2 with ab101272 at 1/1000 (1µg/ml).
    • Detection of L3MBTL2 in Immunoprecipitates of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab101272 at 3 µg/mg lysate for IP (Lane 1). An anti-L3MBTL2 antibody which recognizes an upstream epitope was used in Lane 2, and also for the subsequent WB detection at 1 µg/ml. Lane 3 represents control IgG. Detection: Chemiluminescence with an exposure time of 30 seconds.

    Anti-L3MBTL2 antibody (ab101272)参考文献

    ab101272 has not yet been referenced specifically in any publications.

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