概述

  • 产品名称Kynurenic acid
  • 描述
    Endogenous ionotropic / nicotinic antagonist
  • 生物学描述Endogenous antagonist at ionotropic, glycine β and α7 nicotinic receptors. Neuroprotective in vivo. Water-soluble form available - please see Kynurenic acid sodium salt (ab120256)
  • 纯度> 99%

性能

    相关产品

    Kynurenic acid 图像

    • C1 and C2 - Inhibition of climbing fiber to Purkinje cell EPSCs in (control; black) by 1 mM Kynurenic acid (red, ab120064) or 100 nM NBQX (green, ab120045) recorded in 2.5 mM external Ca2+ at 0.05 Hz (C1) and 2 Hz (C2) stimulation frequency. D - Summary of inhibition of EPSCs by 1 mM Kynurenic acid (red, ab120064) and 100 nM NBQX (green, ab120045) in 2.5 mM external Ca2+.

    Kynurenic acid (ab120064)参考文献

    This product has been referenced in:
    • Grilli M  et al. Modulation of the function of presynaptic alpha7 and non-alpha7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brain. Br J Pharmacol 149:724-32 (2006). Read more (PubMed: 17016503) »
    • Pittaluga A  et al. The "kynurenate test", a biochemical assay for putative cognition enhancers. J Pharmacol Exp Ther 283:82-90 (1997). Read more (PubMed: 9336311) »
    • Hicks RR  et al. Kynurenate is neuroprotective following experimental brain injury in the rat. Brain Res 655:91-6 (1994). Read more (PubMed: 7812795) »

    See all 23 Publications for this product

    Product Wall

    Thank you for your call yesterday and for your patience while I've been in touch with the lab regarding your enquiry.

    We don't test the extinction coefficient in house, but my colleagues in the lab have found the following regarding the extin...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"