概述

  • 产品名称Anti-Kv2.2抗体[S37-89]
    参阅全部 Kv2.2 一抗
  • 描述
    小鼠单克隆抗体[S37-89] to Kv2.2
  • 经测试应用适用于: IHC-P, IHC-Fr, ICC, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Fusion protein, corresponding to amino acids 1-61 of Rat Kv2.2 (Q63099).

  • 阳性对照
    • Rat brain lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号S37-89
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
ICC Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 1 - 10 µg/ml.

靶标

  • 功能Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
  • 序列相似性Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
  • 结构域The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • delayed rectifier potassium channel protein antibody
    • KCNB2 antibody
    • KCNB2_HUMAN antibody
    • potassium channel Kv2.2 antibody
    • potassium voltage gated channel subfamily B member 2 antibody
    • Potassium voltage-gated channel subfamily B member 2 antibody
    • Voltage-gated potassium channel subunit Kv2.2 antibody
    see all

Anti-Kv2.2 antibody [S37-89] 图像

  • Immunohistochemical detection of Kv2.2 in frozen sections of Mouse brain extract using ab106517.

Anti-Kv2.2 antibody [S37-89] (ab106517)参考文献

This product has been referenced in:
  • Liu DH  et al. Voltage dependent potassium channel remodeling in murine intestinal smooth muscle hypertrophy induced by partial obstruction. PLoS One 9:e86109 (2014). WB ; Mouse . Read more (PubMed: 24516526) »

See 1 Publication for this product

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