Anti-Kv2.2抗体(ab37195)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to Kv2.2
  • 经测试应用
    适用于: WB, IHC-FoFr, IHC-Frmore details
  • 种属反应性
    与反应: Rat, Xenopus laevis
  • 免疫原

    Peptide from the Kv2.2 subunit region of Xenopus and rodent, conjugated to KLH.

  • 阳性对照
    • rat brain

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 50% Glycerol, 0.1% BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab37195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 102 kDa.
IHC-FoFr 1/800.
IHC-Fr 1/1000.

靶标

  • 功能
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.
  • 序列相似性
    Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
  • 结构域
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • 翻译后修饰
    Phosphorylated.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • delayed rectifier potassium channel protein antibody
    • KCNB2 antibody
    • KCNB2_HUMAN antibody
    • potassium channel Kv2.2 antibody
    • potassium voltage gated channel subfamily B member 2 antibody
    • Potassium voltage-gated channel subfamily B member 2 antibody
    • Voltage-gated potassium channel subunit Kv2.2 antibody
    see all

图片

  • Immunohistochemistical detection of Kv2.2 antibody (ab37195) in PFA perfusion-fixed rat cortex sections. ab37195 was used at a dilution of 1/800, incubated for 18 hours @ 20°C in PBS-T 0.3%. Secondary antibody: Alexa Fluor® 488 anti-IgG Rabbit (1/1000). The staining is located in the processes of some neurons as expected.

    See Abreview

文献

ab37195 has not yet been referenced specifically in any publications.

客户评价及客户问答

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Rat Tissue sections (cortex)
Specification
cortex
Fixative
Paraformaldehyde
Permeabilization
No
Username

Dr. Karine Thibault

Verified customer

提交于 Oct 13 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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