Anti-Kv1.6抗体[S19-36] (ab110120)

概述

  • 产品名称Anti-Kv1.6抗体[S19-36]
    参阅全部 Kv1.6 一抗
  • 描述
    小鼠单克隆抗体[S19-36] to Kv1.6
  • 特异性ab110120 does not cross react with other Kv1 channels.
  • 经测试应用适用于: WB, IHC-P, IHC-Fr, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Cow
  • 免疫原

    Synthetic peptide:

    RERRSSYLPTPHRAYAEKR

    , corresponding to C terminal amino acids 507-525 of Rat Kv1.6.

  • 阳性对照
    • Rat brain lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.09% Sodium azide
    Constituents: 50% PBS, 50% Glycerol
  • Concentration information loading...
  • 纯度IgG fraction
  • 纯化说明ab110120 is PEG Purified.
  • 克隆单克隆
  • 克隆编号S19-36
  • 同种型IgG3
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110120 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 1 - 10 µg/ml.

靶标

  • 功能Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • 序列相似性Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.6/KCNA6 sub-subfamily.
  • 结构域The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HBK 2 antibody
    • HBK2 antibody
    • Human brain potassium channel 2 antibody
    • KCNA 6 antibody
    • Kcna6 antibody
    • KCNA6_HUMAN antibody
    • Potassium voltage gated channel shaker related subfamily member 6 antibody
    • Potassium voltage gated channel subfamily A member 6 antibody
    • Potassium voltage-gated channel subfamily A member 6 antibody
    • Voltage gated potassium channel protein Kv1.6 antibody
    • Voltage gated potassium channel subunit Kv1.6 antibody
    • Voltage-gated potassium channel HBK2 antibody
    • Voltage-gated potassium channel subunit Kv1.6 antibody
    see all

Anti-Kv1.6 antibody [S19-36] 图像

  • Immunohistochemical detection of Kv1.6 in frozen sections of Mouse brain extract using ab110120.

Anti-Kv1.6 antibody [S19-36] (ab110120)参考文献

ab110120 has not yet been referenced specifically in any publications.

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