Anti-Kv1.4抗体[S13-31] (ab99332)

概述

  • 产品名称Anti-Kv1.4抗体[S13-31]
    参阅全部 Kv1.4 一抗
  • 描述
    小鼠单克隆抗体[S13-31] to Kv1.4
  • 特异性Specificity: 98%. No cross reactivity against Kv1.1, Kv1.2, Kv1.3, Kv1.5, and Kv1.6 expressed in transfected cells.
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    NSHMPYGYAAQARARERERLAHSR

    , corresponding to amino acids 14-37 of Rat Kv1.4 (P15385).

  • 阳性对照
    • Rat brain lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20ºC.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号S13-31
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab99332 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
ICC/IF Use a concentration of 1 - 10 µg/ml.

靶标

  • 功能Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • 序列相似性Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
  • 结构域The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Voltage gated K+ channel HuKII antibody
    • Fetal skeletal muscle potassium channel antibody
    • HBK4 antibody
    • HK1 antibody
    • HPCN2 antibody
    • HUKII antibody
    • Kcna4 antibody
    • KCNA4_HUMAN antibody
    • KCNA4L antibody
    • KCNA8 antibody
    • kv1.4 antibody
    • PCN2 antibody
    • Potassium channel 2 antibody
    • Potassium voltage gated channel shaker related subfamily member 4 antibody
    • Potassium voltage gated channel subfamily A member 4 antibody
    • Potassium voltage-gated channel subfamily A member 4 antibody
    • Rapidly inactivating potassium channel antibody
    • Shaker related potassium channel Kv1.4 antibody
    • Type A potassium channel antibody
    • Voltage gated potassium channel HBK4 antibody
    • Voltage gated potassium channel HK1 antibody
    • Voltage gated potassium channel subunit Kv1.4 antibody
    • Voltage-gated K(+) channel HuKII antibody
    • Voltage-gated potassium channel HBK4 antibody
    • Voltage-gated potassium channel HK1 antibody
    • Voltage-gated potassium channel subunit Kv1.4 antibody
    see all

Anti-Kv1.4 antibody [S13-31] 图像

  • Immunohistochemical detection of Kv1.4 using ab99332 in Mouse brain. Weak positivity of some neurons with a bit of non-specImmunofluorescentic background.

Anti-Kv1.4 antibody [S13-31] (ab99332)参考文献

ab99332 has not yet been referenced specifically in any publications.

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