概述

  • 产品名称
  • 描述
    兔多克隆抗体to Kv1.2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 450-479 of Human Kv1.2 (NP_004965.1).

  • 阳性对照
    • CEM cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab123570 was purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab123570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 57 kDa.

靶标

  • 相关性
    Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • 细胞定位
    Membrane; Multi-pass membrane protein
  • 数据库链接
  • 别名
    • Akr6a4 antibody
    • BK2 antibody
    • HBK5 antibody
    • HK4 antibody
    • HUKIV antibody
    • Kca1 2 antibody
    • kcna2 antibody
    • KV1.2 antibody
    • MGC50217 antibody
    • Mk 2 antibody
    • MK2 antibody
    • NGK1 antibody
    • Potassium voltage gated channel shaker related subfamily member 2 antibody
    • Potassium voltage-gated channel subfamily A member 2 antibody
    • RBK2 antibody
    • Voltage gated potassium channel subunit Kv1.2 antibody
    see all

图片

  • Anti-Kv1.2 antibody (ab123570) at 1/100 dilution + CEM cell lysate at 35 µg

    Predicted band size : 57 kDa

实验方案

文献

ab123570 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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