Anti-Ku70 + Ku80抗体(ab53126)

概述

  • 产品名称Anti-Ku70 + Ku80抗体
    参阅全部 Ku70 + Ku80 一抗
  • 描述
    兔多克隆抗体to Ku70 + Ku80
  • 特异性ab53126 detects endogenous levels of total Ku70 + Ku80 proteins.
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    A synthetic peptide derived from human Ku70 + Ku80.

  • 阳性对照
    • LoVo cell extracts and human breast carcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab53126 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab53126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
ELISA
  • 应用说明ELISA: 1/20000.
    IHC-P: 1/50 - 1/100.
    WB: 1/300 - 1/1000. Detects bands of approximately 70 and 83 kDa (predicted molecular weight: 70 and 83 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    • 细胞定位Nuclear
    • 数据库链接
    • 别名
      • CTC75 antibody
      • CTC85 antibody
      • CTCBF antibody
      • DNA repair protein XRCC5 antibody
      • DNA repair protein XRCC6 antibody
      • G22P1 antibody
      • G22P2 antibody
      • KARP1 antibody
      • Ku 70 antibody
      • Ku 80 antibody
      • Ku 86 antibody
      • Ku86 antibody
      • ML8 antibody
      • NFIV antibody
      • TLAA antibody
      • XRCC5 antibody
      • XRCC6 antibody
      see all

    Anti-Ku70 + Ku80 antibody 图像

    • All lanes : Anti-Ku70 + Ku80 antibody (ab53126) at 1/300 dilution

      Lane 1 : LoVo cell extract
      Lane 2 : LoVo cell extract with immunising peptide


      Predicted band size : 70 , 83 kDa
    • ab53126 at 1/50 dilution staining Ku70 + Ku80 in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue in the absence and presence of the immunising peptide.

    Anti-Ku70 + Ku80 antibody (ab53126)参考文献

    ab53126 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"