概述

  • 产品名称
  • 描述
    小鼠单克隆抗体to KRT81
  • 经测试应用
    适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 304-505 of Human KRT81.

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab55407 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC/IF
IHC-P
  • 应用说明
    WB: Use at a concentration of 1-5 µg/ml.
    IF/ICC: Use at a concentration of 10 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 组织特异性
      Abundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.
    • 疾病相关
      Defects in KRT81 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
    • 序列相似性
      Belongs to the intermediate filament family.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 1 antibody
      • basic antibody
      • ghHb 1 antibody
      • ghHb1 antibody
      • ghHkb 1 antibody
      • ghHKb1 antibody
      • hair antibody
      • Hair keratin K2.9 antibody
      • Hard keratin type II 1 antibody
      • HB 1 antibody
      • HB1 antibody
      • hHAKB2 1 antibody
      • K2.9 antibody
      • K81 antibody
      • Keratin 81 antibody
      • Keratin antibody
      • Keratin hair basic 1 antibody
      • Keratin type II cuticular Hb1 antibody
      • Keratin-81 antibody
      • Keratin81 antibody
      • KRT 81 antibody
      • KRT81 antibody
      • KRT81_HUMAN antibody
      • KRTHB 1 antibody
      • KRTHB1 antibody
      • Metastatic lymph node 137 gene protein antibody
      • MLN 137 antibody
      • MLN137 antibody
      • type II cuticular Hb1 antibody
      • Type II hair keratin Hb1 antibody
      • Type-II keratin Kb21 antibody
      see all

    图片

    • KRT81 antibody (ab55407) used in immunofluorescence at 10ug/ml on HeLa cells.
    • KRT81 antibody (ab55407) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human esophagus.


    • Predicted band size : 55 kDa
      KRT81 antibody (ab55407) at 1ug/lane + HepG2 cell lysate at 25ug/lane.

    文献

    ab55407 has not yet been referenced specifically in any publications.

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    There are currently no Customer reviews or Questions for ab55407.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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