Anti-KMT4 / Dot1L抗体(ab95128)

概述

  • 产品名称Anti-KMT4 / Dot1L抗体
    参阅全部 KMT4 / Dot1L 一抗
  • 描述
    兔多克隆抗体to KMT4 / Dot1L
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 1000-1050 of Human KMT4/ Dot1L (NP_115871.1).

  • 阳性对照
    • Human Breast Carcinoma, Colon Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Cancer, Ovarian Carcinoma and Prostate Carcinoma

性能

应用

Our Abpromise guarantee covers the use of ab95128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.

靶标

  • 功能Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
  • 序列相似性Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
    Contains 1 DOT1 domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Disrupter of telomere silencing protein 1 antibody
    • DOT 1 antibody
    • DOT1 antibody
    • DOT1 like antibody
    • DOT1 like histone H3 methyltransferase (S. cerevisiae) antibody
    • DOT1 like histone H3 methyltransferase antibody
    • DOT1 like histone H3K79 methyltransferase antibody
    • DOT1 like protein antibody
    • DOT1, S. cerevisiae, homolog of antibody
    • DOT1-like protein antibody
    • DOT1L antibody
    • DOT1L_HUMAN antibody
    • EC 2.1.1.43 antibody
    • H3 K79 HMTase antibody
    • H3 lysine-79 specific antibody
    • H3-K79-HMTase antibody
    • Histone H3 K79 methyltransferase antibody
    • Histone H3 methyltransferase antibody
    • Histone H3 methyltransferase DOT1-like antibody
    • Histone H3-K79 methyltransferase antibody
    • Histone lysine N methyltransferase H3 lysine 79 specific antibody
    • Histone methyltransferase DOT1L antibody
    • Histone-lysine N-methyltransferase antibody
    • KIAA1814 antibody
    • KMT4 antibody
    • Lysine N methyltransferase 4 antibody
    • Lysine N-methyltransferase 4 antibody
    see all

Anti-KMT4 / Dot1L antibody 图像

  • ab95128, at 1/100 dilution, staining KMT4 / Dot1L in formalin-fixed, paraffin-embedded Human colon carcinoma by Immunohistochemistry, using DAB staining.
  • ab95128, at 1/100 dilution, staining KMT4 / Dot1L in formalin-fixed, paraffin-embedded Human breast carcinoma by Immunohistochemistry, using DAB staining.

Anti-KMT4 / Dot1L antibody (ab95128)参考文献

ab95128 has not yet been referenced specifically in any publications.

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