Anti-KMT3C / SMYD2抗体- N-terminal (ab71235)

概述

  • 产品名称Anti-KMT3C / SMYD2抗体- N-terminal
    参阅全部 KMT3C / SMYD2 一抗
  • 描述
    兔多克隆抗体to KMT3C / SMYD2 - N-terminal
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide at the N terminal region of human KMT3C/ SMYD2 conjugated to KLH

  • 阳性对照
    • 293 cell lysate transiently transfected with the KMT3C / SMYD2 gene.

性能

应用

Our Abpromise guarantee covers the use of ab71235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

靶标

  • 功能Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB.
  • 序列相似性Contains 1 MYND-type zinc finger.
    Contains 1 SET domain.
  • 细胞定位Cytoplasm > cytosol. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Histone methyltransferase SMYD2 antibody
    • HSKM B antibody
    • HSKM-B antibody
    • HSKMB antibody
    • KMT3C antibody
    • Lysine N-methyltransferase 3C antibody
    • MGC119305 antibody
    • N lysine methyltransferase SMYD2 antibody
    • N-lysine methyltransferase SMYD2 antibody
    • SET and MYND domain containing 2 antibody
    • SET and MYND domain containing protein 2 antibody
    • SET and MYND domain-containing protein 2 antibody
    • Smyd2 antibody
    • SMYD2_HUMAN antibody
    • Zinc finger MYND domain containing 14 antibody
    • ZMYND14 antibody
    see all

Anti-KMT3C / SMYD2 antibody - N-terminal 图像

  • All lanes : Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235) at 1/50 dilution

    Lane 1 : 293 cell lysates (non transfected)
    Lane 2 : 293 cell lysates transiently transfected with the KMT3C / SMYD2 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 50 kDa
    Observed band size : 50 kDa

Anti-KMT3C / SMYD2 antibody - N-terminal (ab71235)参考文献

ab71235 has not yet been referenced specifically in any publications.

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