概述

  • 产品名称
    Anti-KLRA2抗体
  • 描述
    兔多克隆抗体to KLRA2
  • 经测试应用
    适用于: ICC/IF, WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    14 amino acid synthetic peptide near the C-terminus of Mouse KLRA2

  • 阳性对照
    • Mouse spleen tissue lysate, Human spleen tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab107510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 34 kDa.
IHC-P Use a concentration of 2.5 µg/ml.

靶标

  • 相关性
    KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells.
  • 细胞定位
    Membrane
  • 数据库链接
  • 别名
    • Ly49-b antibody
    • Killer cell lectin-like receptor 2 antibody
    • Klra2 antibody
    • Ly-49b antibody
    • Ly49b antibody
    • Lymphocyte antigen 49b antibody
    • T-cell surface glycoprotein Ly-49B antibody
    see all

图片

  • Lane 1 : Anti-KLRA2 antibody (ab107510) at 0.5 µg/ml
    Lane 2 : Anti-KLRA2 antibody (ab107510) at 1 µg/ml

    Lane 1 : Mouse spleen tissue lysate
    Lane 2 : Mouse spleen tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 34 kDa
  • Immunohistochemistry of KLRA2 in paraffin embedded mouse spleen tissue with ab107510 at 2.5 µg/ml.

文献

ab107510 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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